ArticleThoracic cancer2017
Logistic regression analysis of the risk factors of anastomotic fistula after radical resection of esophageal-cardiac cancer.
Article in Thoracic cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- The treatments and postoperative complications of esophageal cancer: a review.Journal of cardiothoracic surgery · 2020Pooled it
- Association of perioperative cholesterol depletion with anastomotic leak after esophagectomy for cancer: a retrospective study.Journal of thoracic disease · 2025Article
- Expression and clinical significance of BUB1 in esophageal cancer.American journal of translational research · 2025Article
- Mediastinal drainage combined with upper mediastinal re-tunneling vs. mediastinal drainage alone in McKeown esophagectomy of esophageal cancer: a retrospective study.Frontiers in surgery · 2024Article
- Developing a new predictive index for anastomotic leak following the anastomosis of esophageal atresia: preliminary results from a single centre.Journal of cardiothoracic surgery · 2022Review
- Difference between delayed anastomosis and early anastomosis in damage control laparotomy affecting the infusion volume and NPWT output volume: is infusion restriction necessary in delayed anastomosis? A single-center retrospective analysis.Trauma surgery & acute care open · 2022Article
- Risk factors for anastomotic complications after one-stage anastomosis for oesophageal atresia.Journal of cardiothoracic surgery · 2021Article
- Risk Factors of Cervical Anastomotic Leakage after McKeown Minimally Invasive Esophagectomy: Focus on Preoperative and Intraoperative Lung Function.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2021Article
- A Novel Nomogram for Prediction of Early Postoperative Complications of Total Gastrectomy for Gastric Cancer.Cancer management and research · 2021Article
- Constructing a risk prediction model for anastomotic leakage after esophageal cancer resection.The Journal of international medical research · 2020Article
- Application of pleural flaps in laparoscopic-thoracoscopic esophagectomy for esophageal cancer.Journal of thoracic disease · 2020Article
- Development and validation of a risk prediction model for radiotherapy-related esophageal fistula in esophageal cancer.Radiation oncology (London, England) · 2019Article
- A new technology for reducing anastomotic fistula in the neck after esophageal cancer surgery.Journal of thoracic disease · 2019Article
- C-reactive protein to albumin ratio is a key indicator in a predictive model for anastomosis leakage after esophagectomy: Application of classification and regression tree analysis.Thoracic cancer · 2019Article
- Ischaemic conditioning of the stomach previous to esophageal surgery.Journal of thoracic disease · 2019Review
- Prediction model using risk factors associated with anastomotic leakage after minimally invasive esophagectomy.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was conducted to investigate the risk factors of anastomotic fistula after the radical resection of esophageal-cardiac cancer.
methodsFive hundred and forty-four esophageal-cardiac cancer patients who underwent surgery and had complete clinical data were included in the study. Fifty patients diagnosed with postoperative anastomotic fistula were considered the case group and the remaining 494 subjects who did not develop postoperative anastomotic fistula were considered the control. The potential risk factors for anastomotic fistula, such as age, gender, diabetes history, smoking history, were collected and compared between the groups. Statistically significant variables were substituted into logistic regression to further evaluate the independent risk factors for postoperative anastomotic fistulas in esophageal-cardiac cancer.
resultsThe incidence of anastomotic fistulas was 9.2% (50/544). Logistic regression analysis revealed that female gender (P < 0.05), laparoscopic surgery (P < 0.05), decreased postoperative albumin (P < 0.05), and postoperative renal dysfunction (P < 0.05) were independent risk factors for anastomotic fistulas in patients who received surgery for esophageal-cardiac cancer. Of the 50 anastomotic fistulas, 16 cases were small fistulas, which were only discovered by conventional imaging examination and not presenting clinical symptoms. All of the anastomotic fistulas occurred within seven days after surgery. Five of the patients with anastomotic fistulas underwent a second surgery and three died.
conclusionFemale patients with esophageal-cardiac cancer treated with endoscopic surgery and suffering from postoperative hypoproteinemia and renal dysfunction were susceptible to postoperative anastomotic fistula.
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