ArticleEuropean journal of neurology2018
Long-term effects of cognitive rehabilitation on brain, functional outcome and cognition in Parkinson's disease.
Article in European journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- The use of combined cognitive training and non-invasive brain stimulation to modulate impulsivity in adult populations: a systematic review and meta-analysis of existing studies.Frontiers in psychiatry · 2024Pooled it
- Cognitive training interventions for dementia and mild cognitive impairment in Parkinson's disease.The Cochrane database of systematic reviews · 2020Pooled it
- Effects of immersive virtual reality and adaptive cognitive training on cognition and function in parkinson's disease mild cognitive impairment: a randomized clinical trial.Scientific reports · 2026Trial
- A randomized comparative feasibility study of neuromodulation and cognitive training for post-COVID fatigue.Scientific reports · 2025Trial
- Early implementation of intended exercise improves quality of life in Parkinson's disease patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Trial
- Predicting Parkinson's disease and its progression based on radiomics in T1-weight images and α‑synuclein in cerebrospinal fluid.NPJ Parkinson's disease · 2025Article
- Spatial memory deficits in Parkinson's disease: neural mechanisms and assessment.American journal of neurodegenerative disease · 2025Review
- Towards a Non-pharmacological Intervention on Apathy in Korsakoff's Syndrome: A Systematic Narrative Review Across Different Clinical Conditions.Neuropsychiatric disease and treatment · 2024Review
- Long-term effects of cognitive training in Parkinson's disease: A randomized, controlled trial.Clinical parkinsonism & related disorders · 2023Article
- Sex Differences in Brain Structure in de novo Parkinson's Disease: A Cross-Sectional and Longitudinal Neuroimaging Study.Journal of Parkinson's disease · 2023Article
- Efficacy and Feasibility of Remote Cognitive Remediation Therapy in Parkinson's Disease: A Randomized Controlled Trial.Parkinson's disease · 2023Article
- Apathy in Parkinson's Disease: Defining the Park Apathy Subtype.Brain sciences · 2022Review
- Cognitive Training in Parkinson's Disease Induces Local, Not Global, Changes in White Matter Microstructure.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Article
- Exercise Management Using a Mobile App in Patients With Parkinsonism: Prospective, Open-Label, Single-Arm Pilot Study.JMIR mHealth and uHealth · 2021Article
- A Scoping Review of Cognitive Training in Neurodegenerative Diseases via Computerized and Virtual Reality Tools: What We Know So Far.Brain sciences · 2021Article
- Optimizing Cognitive Training for the Treatment of Cognitive Dysfunction in Parkinson's Disease: Current Limitations and Future Directions.Frontiers in aging neuroscience · 2021Review
- Resting-State Functional Magnetic Resonance Imaging Networks as a Quantitative Metric for Impact of Neurosurgical Interventions.Frontiers in neuroscience · 2021Article
- Functional and Cognitive Improvement After an Intensive Inpatient Multidisciplinary Rehabilitation Program in Mild to Severe Parkinson's Disease: A Retrospective and Observational Study.Frontiers in neurology · 2021Article
- Rationale and Design of the PAIRED Trial: Partnered Dance Aerobic Exercise as a Neuroprotective, Motor, and Cognitive Intervention in Parkinson's Disease.Frontiers in neurology · 2020Article
- Resting-state Functional MRI in Parkinsonian Syndromes.Movement disorders clinical practice · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeCognitive rehabilitation has demonstrated efficacy in producing short-term cognitive and brain changes in patients with Parkinson's disease (PD). To date, no study has assessed the long-term effects of cognitive rehabilitation using neuroimaging techniques in PD. The aim was to assess the longitudinal effects of a 3-month cognitive rehabilitation programme evaluating the cognitive, behavioural and neuroimaging changes after 18 months.
methodsFifteen patients with PD underwent a cognitive, behavioural and neuroimaging assessment at pre-treatment (T
resultsPatients with PD showed increased cognitive performance, decreased functional disability, increased brain FC and activation at T
conclusionsFindings suggest that the improved cognitive performance and increased brain FC and activation after cognitive rehabilitation were significantly maintained after 18 months in patients with PD, despite the structural brain changes, consistent with a progression of neurodegenerative processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.