ArticleMedical physics2017
Improved quantitative
Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
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- Deep learning-guided attenuation and scatter correction ofAnnals of nuclear medicine · 2026Article
- CT-free attenuation and Monte-Carlo based scatter correction-guided quantitativeEuropean journal of nuclear medicine and molecular imaging · 2025Article
- An Evaluation of 90Y Bremsstrahlung SPECT Image Quality in the Presence of 99mTc: A Technical Perspective on Same-Day Radioembolization.Current oncology (Toronto, Ont.) · 2024Article
- Radiomics and Artificial Intelligence in Radiotheranostics: A Review of Applications for Radioligands Targeting Somatostatin Receptors and Prostate-Specific Membrane Antigens.Diagnostics (Basel, Switzerland) · 2024Review
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- 90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework.EJNMMI physics · 2023Article
- Physics-Guided Deep Scatter Estimation by Weak Supervision for Quantitative SPECT.IEEE transactions on medical imaging · 2023Article
- Voxel-S-value methods adapted to heterogeneous media for quantitative Y-90 microsphere radioembolization dosimetry.Zeitschrift fur medizinische Physik · 2023Article
- Article
- Investigation and optimization of PET-guided SPECT reconstructions for improved radionuclide therapy dosimetry estimates.Frontiers in nuclear medicine · 2023Article
- Tumor Response to Radiopharmaceutical Therapies: The Knowns and the Unknowns.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Review
- EANM dosimetry committee series on standard operational procedures: a unified methodology forEJNMMI physics · 2021Article
- Standardizing SPECT/CT dosimetry following radioembolization with yttrium-90 microspheres.EJNMMI physics · 2021Article
- Comparison ofPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021Article
- Current Status of Radiopharmaceutical Therapy.International journal of radiation oncology, biology, physics · 2021Review
- Relationship of radiation dose to efficacy of radioembolization of liver metastasis from breast cancer.European journal of radiology · 2021Article
- Quantitative imaging of bone remodeling in patients with a unicompartmental joint unloading knee implant (ATLAS Knee System)-effect of metal artifacts on a SPECT-CT-based quantification.EJNMMI physics · 2021Article
- Recent advances in voxel-based targeted radionuclide therapy dosimetry.Quantitative imaging in medicine and surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeIn
methodsSince a fully Monte Carlo (MC) approach to
resultsThere was convergence of the scatter estimate after just two updates, greatly reducing computational requirements. In the phantom study, compared with reconstruction without scatter correction, with MC scatter modeling there was substantial improvement in activity recovery in intrahepatic lesions (from > 55% to > 86%), normal liver (from 113% to 104%), and lungs (from 227% to 104%) with only a small degradation in noise (13% vs. 17%). Similarly, with scatter modeling contrast improved substantially both visually and in terms of a detectability index, which was especially relevant for the low uptake extrahepatic objects. The trends observed for the phantom were also seen in the patient studies where lesion activity concentrations and lesion-to-liver concentration ratios were lower for SPECT without scatter correction compared with reconstruction with just two MC scatter updates: in eleven lesions the mean uptake was 4.9 vs. 7.1 MBq/mL (P = 0.0547), the mean normal liver uptake was 1.6 vs. 1.5 MBq/mL (P = 0.056) and the mean lesion-to-liver uptake ratio was 2.7 vs. 4.3 (P = 0.0402) for reconstruction without and with scatter correction respectively.
conclusionsQuantitative accuracy of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.