ArticleJournal of the American Geriatrics Society2018
Prevalence of Long-Term Opioid Use in Long-Stay Nursing Home Residents.
Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Predictors and Clinical Outcomes of Long-Term Opioid Therapy in Older Adults: A Systematic Review.Pharmacotherapy · 2026Pooled it
- Current Psychotropic Medication Use and Contributing Factors Among Nursing Home Residents With Cognitive Impairment.Clinical nursing research · 2021Trial
- Identifying observable medication use time in administrative databases: a tutorial using nursing home residents.American journal of epidemiology · 2026Article
- Risk of Seizure Associated With Concomitant Use of Tramadol and Antidepressants in Older Nursing Home Residents.Neurology · 2025Article
- Prescription drug monitoring programs and perioperative opioid prescribing and adverse events.Health affairs scholar · 2025Article
- Preliminary Evidence Supporting Validity and Reliability of the Assessment for Appropriate Use of Opioids for Long-Term Care.The Senior care pharmacist · 2025Article
- Association of initiating CYP2D6-metabolized opioids with risks of adverse outcomes in older adults receiving antidepressants: A retrospective cohort study.PLoS medicine · 2025Article
- Factors associated with long-term opioid use among patients with axial spondyloarthritis or psoriatic arthritis who initiate opioids.Rheumatology (Oxford, England) · 2025Article
- Relationship between medication safety-related processes and medication use in residential aged care facilities.Australasian journal on ageing · 2024Article
- Differences in Medication Use by Gender and Race in Hospitalized Persons Living with Dementia.Journal of racial and ethnic health disparities · 2024Article
- Prescribing Trends and Associated Outcomes of Antiepileptic Drugs and Other Psychotropic Medications in US Nursing Homes: Proposal for a Mixed Methods Investigation.JMIR research protocols · 2024Article
- Clinical and Adverse Outcomes Associated With Concomitant Use of CYP2D6-Metabolized Opioids With Antidepressants in Older Nursing Home Residents : A Target Trial Emulation Study.Annals of internal medicine · 2024Article
- Prevalence of Opioid Use in Nursing Homes Over the Last Decade: A Systematic Literature Review.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2024Article
- Racial Disparities in Opioid Prescribing in the United States from 2011 to 2021: A Systematic Review and Meta-Analysis.Journal of pain research · 2024Review
- Comparative safety of adding serotonin and norepinephrine reuptake inhibitors (SNRIs) versus nonsteroidal anti-inflammatory drugs (NSAIDs) to short-acting opioids for non-malignant pain in nursing homes.Journal of the American Geriatrics Society · 2023Article
- Trends in Antiseizure Medication Prescribing Among Nursing Home Residents With and Without a Seizure Diagnosis.The neurologist · 2023Article
- Pain, Opioid Analgesics, and Cognition: A Conceptual Framework in Older Adults.Pain medicine (Malden, Mass.) · 2023Article
- Correlates of Opioid Use Among Ontario Long-Term Care Residents and Variation by Pain Frequency and Intensity: A Cross-sectional Analysis.Drugs & aging · 2022Article
- Opioids in the Elderly Patients with Cognitive Impairment: A Narrative Review.Pain and therapy · 2022Review
- Prevalence of constipation and use of laxatives, and association with risk factors among older patients during hospitalization: a cross sectional study.BMC gastroenterology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectivesOverall and long-term opioid use among older adults have increased since 1999. Less is known about opioid use in older adults in nursing homes (NHs).
designCross-sectional.
settingU.S. NHs (N = 13,522).
participantsLong-stay NH resident Medicare beneficiaries with a Minimum Data Set 3.0 (MDS) assessment between April 1, 2012, and June 30, 2012, and 120 days of follow-up (N = 315,949). MEASUREMENTS: We used Medicare Part D claims to measure length of opioid use in the 120 days from the index assessment (short-term: ≤30 days, medium-term: >30-89 days, long-term: ≥90 days), adjuvants (e.g., anticonvulsants), and other pain medications (e.g., corticosteroids). MDS assessments in the follow-up period were used to measure nonpharmacological pain management use. Modified Poisson models were used to estimate adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) for age, gender, race and ethnicity, cognitive and physical impairment, and long-term opioid use.
resultsOf all long-stay residents, 32.4% were prescribed any opioid, and 15.5% were prescribed opioids long-term. Opioid users (versus nonusers) were more commonly prescribed pain adjuvants (32.9% vs 14.9%), other pain medications (25.5% vs 11.0%), and nonpharmacological pain management (24.5% vs 9.3%). Long-term opioid use was higher in women (aPR = 1.21, 95% CI = 1.18-1.23) and lower in racial and ethnic minorities (non-Hispanic blacks vs whites: APR = 0.93, 95% CI = 0.90-0.94) and those with severe cognitive impairment (vs no or mild impairment, aPR = 0.82, 95% CI = 0.79-0.83).
conclusionOne in seven NH residents was prescribed opioids long-term. Recent guidelines on opioid prescribing for pain recommend reducing long-term opioid use, but this is challenging in NHs because residents may not benefit from nonpharmacological and nonopioid interventions. Studies to address concerns about opioid safety and effectiveness (e.g., on pain and functional status) in NHs are needed.
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Registered trials
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