Evidence map›Paper›PMID 28940183›Full record

ArticleClinical and experimental immunology2018

An increased CD25-positive intestinal regulatory T lymphocyte population is dependent upon Cox-2 activity in the Apc

O O Faluyi, P Fitch, S E M Howie

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Prostaglandin EProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. YYFZBJS ameliorates colorectal cancer progression in ApcCell communication and signaling : CCS · 2020
    Article
  7. Role of prostanoids in gastrointestinal cancer.The Journal of clinical investigation · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

O O FaluyiEdinburgh Cancer Centre, Western General Hospital, Edinburgh, UK.ORCID 0000-0001-6710-2210
P FitchMRC Centre for Inflammation Research, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, UK.
S E M HowieMRC Centre for Inflammation Research, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, UK.
Centre for Inflammation Research · GBWestern General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Only mismatch repair (MMR)-deficient colorectal cancer (CRC) appears to respond well to programmed death (PD)-1 inhibition at the present time. Emerging evidence suggests a role for micro-environmental factors such as CD25

Indexed as

Genes, APCAnimalsBiomarkersCell Transformation, NeoplasticColorectal NeoplasmsCyclooxygenase 2CytokinesDisease Models, AnimalForkhead Transcription FactorsImmunohistochemistryImmunophenotypingInterleukin-2 Receptor alpha SubunitIntestinal MucosaMiceMice, KnockoutMucosal-Associated Invariant T CellsBiomarkersCyclooxygenase 2CytokinesForkhead Transcription FactorsFoxp3 protein, mouseInterleukin-2 Receptor alpha SubunitThymic Stromal LymphopoietinTransforming Growth Factor betaTSLP protein, mouseCox-2intestineregulatory T cellTGF-βtumorigenesis

Identifiers

PMID28940183
PMCPMC5721251
OpenAlexW2756584782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.