Evidence map›Paper›PMID 28939988›Full record

ArticleJournal of assisted reproduction and genetics2018

Frozen embryo transfer can be performed in the cycle immediately following the freeze-all cycle.

Kemal Ozgur, Hasan Bulut, Murat Berkkanoglu, Peter Humaidan, Kevin Coetzee

Open access · bronzeAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Meta-analysis of the embryo freezing transfer interval.Reproductive medicine and biology · 2021
    Review
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  11. To delay or not frozen embryo transfer in freeze-all cycles?Annals of translational medicine · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kemal OzgurAntalya IVF, Halide Edip Cd. No:7, Kanal Mh, 07080, Antalya, Turkey.
Hasan BulutAntalya IVF, Halide Edip Cd. No:7, Kanal Mh, 07080, Antalya, Turkey.
Murat BerkkanogluAntalya IVF, Halide Edip Cd. No:7, Kanal Mh, 07080, Antalya, Turkey.
Peter HumaidanThe Fertility Clinic, Skive Regional Hospital and Faculty of Health, Aarhus University, Aarhus, Denmark.
Kevin CoetzeeAntalya IVF, Halide Edip Cd. No:7, Kanal Mh, 07080, Antalya, Turkey. kevincoetzee61@yahoo.co.nz.ORCID http://orcid.org/0000-0002-8676-7020
Antalya IVF · TRAarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, we investigated whether the time interval between oocyte retrieval and frozen embryo transfer (FET) affected the live birth (LB) rates of human segmented-IVF cycles.

methodA total of 1338 ICSI freeze-all cycles were performed between February 2015 and January 2016, with 1121 FET cycles being retrospectively analyzed. All vitrified-warmed blastocyst transfers were performed in artificial FET cycles, using gonadotropin-releasing hormone (GnRH) agonist downregulation and oral estrogen endometrial preparation. The primary outcome measure was LB. Cycles were investigated in oocyte retrieval-to-FET interval groups of 32-46, 47-61, 62-76, 77-91, and ≥ 92 days, with the 47-61-day group used as the reference group.

resultsThere were no significant differences in LB rates between the groups in the overall analysis, as well as, in sub-analyses investigating LB in terms of single blastocyst transfer (SBT), trigger type (GnRH agonist, triggers including hCG), oocyte number (≤ 5 and ≥ 15), and maternal age (> 35 years).

conclusionThe present study showed that it is feasible to perform transfers 36 days after oocyte retrieval and that delaying FET in freeze-all beyond the cycle immediately following oocyte retrieval does not increase LB rates.

Indexed as

AdultBirth RateCryopreservationEmbryo, MammalianEmbryo TransferFeasibility StudiesFemaleFreezingHumansMenstrual CycleOocyte RetrievalOvulation InductionPregnancyPregnancy RateRetrospective StudiesTime FactorsBlastocystDelayFreeze-allFrozen embryo transferLive birth

Identifiers

PMID28939988
PMCPMC5758470
OpenAlexW2758142137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.