Evidence map›Paper›PMID 28939917›Full record

ArticleHNO2018

Use of a fibrinogen-thrombin sponge in rhinoplasty.

A Berghaus, M San Nicoló, C Jacobi

Abstract read
PubMed Publisher
In one paragraph

Article in HNO, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Fascialage: A Refined Technique of Dorsal Augmentation in Rhinoplasty.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

A BerghausDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Grosshadern Campus Ludwig-Maximilian-University Munich, Marchioninistr. 15, 81377, Munich, Germany. alexander.berghaus@med.uni-muenchen.de.
M San NicolóDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Grosshadern Campus Ludwig-Maximilian-University Munich, Marchioninistr. 15, 81377, Munich, Germany.
C JacobiDepartment of Oto-Rhino-Laryngology, Head and Neck Surgery, Grosshadern Campus Ludwig-Maximilian-University Munich, Marchioninistr. 15, 81377, Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough several methods have been described to address nasal dorsum augmentation and smoothing of irregularities in rhinoplasty, establishing the ideal method has proven controversial.

objectiveHere, we introduce a novel technique of cartilage grafting for nasal dorsum augmentation by wrapping cartilage in a fibrinogen- and thrombin-coated collagen patch called TachoSil®. MATERIAL AND

methodsIn a pilot study comprising ten cases, the use of the collagen patch was examined in various indications in rhinoplasty. Patients were clinically monitored for up to 8 months and photometric and sonographic documentation was performed pre- and postoperatively.

resultsIn nine patients, the collagen patch was used for fixation of cartilage grafts in different indications: saddle nose deformities (n = 5), open roof (n = 1), nasal dorsum irregularities (n = 3). A diced cartilage graft enclosed by a bilayer of TachoSil® was applied in seven patients. Solid pieces of cartilage were either embedded in a bilayer of the collagen patch (n = 1) or covered by a monolayer (n = 1). Moreover, the collagen patch alone served as a soft tissue support in one patient with thin skin. Six patients were revision cases. All patients had uneventful healing without adverse events such as allergic reactions and infections.

conclusionThe collagen patch TachoSil® is eligible for various indications in rhinoplasty. It is a useful material predominantly for nasal dorsum augmentation by sandwiching diced or solid cartilage in the collagen patch, leading to better graft fixation and precise profile shaping. At the same time, TachoSil® helps with blood control. Follow-up studies will be performed to assess the material's long-term behavior.

Indexed as

FibrinogenRhinoplastyHumansPilot ProjectsSurgical EquipmentThrombinFibrinogenThrombinCartilageCosmetic techniquesNasal cartilagesNasal surgical proceduresTissue grafts

Identifiers

PMID28939917
OpenAlexW2757787108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.