Evidence map›Paper›PMID 28939911›Full record

ArticleScientific reports2017

CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.

Kyoung Wan Yoon, Hyun-Suk Yang, Young Mok Kim, Yeonsil Kim, Seongman Kang, Woong Sun, Ulhas P Naik, Leslie V Parise, Eui-Ju Choi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. The Diverse Functions of the Calcium- and Integrin-Binding Protein Family.International journal of molecular sciences · 2025
    Review
  2. The Function of ASK1 in Sepsis and Stress-Induced Disorders.International journal of molecular sciences · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Functions of p38 MAP Kinases in the Central Nervous System.Frontiers in molecular neuroscience · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Kyoung Wan YoonDepartment of Life Sciences, Korea University, Seoul, 02841, Korea.
Hyun-Suk YangDepartment of Biotechnology, Hoseo University, Asan, 31499, Korea.
Young Mok KimDepartment of Life Sciences, Korea University, Seoul, 02841, Korea.
Yeonsil KimDepartment of Life Sciences, Korea University, Seoul, 02841, Korea.
Seongman KangDepartment of Life Sciences, Korea University, Seoul, 02841, Korea.
Woong SunDepartment of Anatomy, Brain Korea 21 Program, Korea University College of Medicine, Seoul, 02841, Korea.ORCID 0000-0003-1792-4894
Ulhas P NaikCardeza Center for Vascular Biology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Leslie V PariseDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Eui-Ju ChoiDepartment of Life Sciences, Korea University, Seoul, 02841, Korea. ejchoi@korea.ac.kr.
Korea University · KRHoseo University · KRThomas Jefferson University · USUniversity of North Carolina at Chapel Hill · US

Funding

ASK1 a novel regulator of platelet functionR01HL113188 · NHLBI · UNIVERSITY OF DELAWARE · PI NAIK, ULHAS P · 2013 to 2022
$3.4M
NHLBI NIH HHS R01 HL113188
6 · The paper itself

Abstract

Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin α

Indexed as

1-Methyl-4-phenylpyridiniumAnimalsApoptosisBrainCalcium-Binding ProteinsCell Line, TumorDisease Models, AnimalDopaminergic NeuronsHumansMAP Kinase Kinase Kinase 5MiceMice, Inbred C57BLMice, KnockoutMPTP PoisoningParkinson DiseasePrimary Cell Culture1-Methyl-4-phenylpyridiniumCalcium-Binding ProteinsCIB1 protein, humanCib1 protein, mouseMAP3K5 protein, humanMap3k5 protein, mouseMAP Kinase Kinase Kinase 5RNA, Small Interfering

Identifiers

PMID28939911
PMCPMC5610320
OpenAlexW2754758908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.