Evidence map›Paper›PMID 28939775›Full record

ArticleThe Journal of biological chemistry2017

Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine.

Jung-Hoon Yoon, Jayati Roy Choudhury, Jeseong Park, Satya Prakash, Louise Prakash

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  6. Review
  7. Article
  8. Article
  9. DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways.International journal of molecular sciences · 2023
    Review
  10. Multifaceted Nature of DNA Polymerase θ.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jung-Hoon YoonFrom the Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1061.
Jayati Roy ChoudhuryFrom the Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1061.
Jeseong ParkFrom the Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1061.
Satya PrakashFrom the Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1061.
Louise PrakashFrom the Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555-1061 l.prakash@utmb.edu.
The University of Texas Medical Branch at Galveston · US

Funding

Synthetic Organic Chemistry CoreP30ES006676 · NIEHS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 1995 to 2017
$21.7M
Role of human DNA polymerase iota in replicative bypass of DNA lesionsR01ES021452 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AGGARWAL, ANEEL K. · 2013 to 2017
$2.2M
Role of cohesin in lesion bypass in DNA damaged human cellsR01ES022948 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, LOUISE · 2014 to 2018
$1.7M
Genetic control of replication through DNA lesions in humans, and carcinogenesisR01ES020833 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, SATYA · 2012 to 2016
$1.7M
NIEHS NIH HHS P30 ES006676NIEHS NIH HHS R01 ES020833NIEHS NIH HHS R01 ES021452NIEHS NIH HHS R01 ES022948
6 · The paper itself

Abstract

N3-Methyladenine (3-MeA) is formed in DNA by reaction with

Indexed as

DNA ReplicationAdenineBiocatalysisCell LineDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase iotaDNA Polymerase thetaDNA RepairHumansIsoenzymesKineticsMutation RateNuclear ProteinsNucleotidyltransferasesRNA Interference3-deaza-3-methyladenineAdenineDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase iotaDNA Polymerase thetaDNA polymerase zetaIsoenzymesNuclear ProteinsNucleotidyltransferasesPOLI protein, humanPOLK protein, humanREV1 protein, humanY-Family DNA PolymerasesDNA damageDNA damage responseDNA enzymeDNA polymeraseDNA repairN3-methyladenine, translesion synthesis in human cells

Identifiers

PMID28939775
PMCPMC5682974
OpenAlexW2758636765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.