Evidence map›Paper›PMID 28939714›Full record

Observational studyJournal of the American Heart Association2017

Kidney Disease Measures and Left Ventricular Structure and Function: The Atherosclerosis Risk in Communities Study.

Kunihiro Matsushita, Lucia Kwak, Yingying Sang, Shoshana H Ballew, Hicham Skali, Amil M Shah, Josef Coresh, Scott Solomon

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
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  4. Myocardial work in chronic kidney disease: insights from the CPH-CKD ECHO Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD kmatsus5@jhmi.edu.
Lucia KwakDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Yingying SangDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Shoshana H BallewDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Hicham SkaliCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Amil M ShahCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Scott SolomonCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure is one of the most important complications of chronic kidney disease (CKD). However, few studies comprehensively investigated left ventricular (LV) structure and function in relation to 2 key CKD measures, estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR). METHODS AND

resultsAmong 4175 ARIC (Atherosclerosis Risk in Communities) participants (aged 66-90 years during 2011-2013), we quantified the association of eGFR and ACR with echocardiogram parameters of LV mass, size, systolic function, and diastolic function. Adjusting for demographic variables, both CKD measures were significantly associated with most echocardiogram parameters. Additionally accounting for other potential confounders, we observed significantly higher LV mass index according to reduced eGFR (82.3 [95% confidence interval (CI), 77.6-87.0] g/m

conclusionsLV mass was related to both CKD measures, whereas LV size and function were robustly associated with albuminuria. These results have implications for pathophysiological processes behind cardiorenal syndrome and targeted cardiac assessment in patients with CKD.

Indexed as

Glomerular Filtration RateVentricular Function, LeftVentricular RemodelingAgedAged, 80 and overAlbuminuriaBiomarkersCreatinineEchocardiography, DopplerFemaleHeart FailureHumansKidneyMaleRenal Insufficiency, ChronicRisk FactorsBiomarkersCreatininealbuminuriacardiac functioncardiac structureepidemiologyglomerular filtration rate

Identifiers

PMID28939714
PMCPMC5634280

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.