ArticleAmerican journal of physiology. Heart and circulatory physiology2018
Notch signaling modulates the electrical behavior of cardiomyocytes.
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Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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0cells of the map it votes in
20citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Homeostatic preservation of action potential waveform by Notch and Nerfin-1.Current biology : CB · 2026Article
- A custom analysis of R-R interval properties reveals alterations in the brain-heart axis in experimental animals with metabolic syndrome.Heart rhythm O2 · 2026Article
- Ion channels and cardiac disease: mechanisms and functions of a disintegrin and metalloproteases and their substrates.Frontiers in cell and developmental biology · 2026Review
- Notch2 Signaling Drives Cardiac Hypertrophy by Suppressing Purine Nucleotide Metabolism.Research (Washington, D.C.) · 2025Article
- The cAMP/PKA signaling pathway conditions cardiac performance in experimental animals with metabolic syndrome.Journal of molecular and cellular cardiology · 2024Article
- Phosphorylation of cardiac sodium channel at Ser571 anticipates manifestations of the aging myopathy.American journal of physiology. Heart and circulatory physiology · 2024Article
- KCells · 2023Review
- A perspective on Notch signalling in progression and arrhythmogenesis in familial hypertrophic and dilated cardiomyopathies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Modulation of Notch Signaling at Early Stages of Differentiation of Human Induced Pluripotent Stem Cells to Dopaminergic Neurons.International journal of molecular sciences · 2023Article
- lncRNA-TCONS_00008552 expression in patients with pulmonary arterial hypertension due to congenital heart disease.PloS one · 2023Article
- The Role of the Notch Signaling Pathway in Recovery of Cardiac Function after Myocardial Infarction.International journal of molecular sciences · 2022Review
- Article
- Heart Rate Variability Reveals Altered Autonomic Regulation in Response to Myocardial Infarction in Experimental Animals.Frontiers in cardiovascular medicine · 2022Article
- Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration.Journal of cardiovascular development and disease · 2021Review
- Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling.JCI insight · 2021Article
- Transcriptomic uniqueness and commonality of the ion channels and transporters in the four heart chambers.Scientific reports · 2021Article
- Analysis of Molecular Mechanism of YiqiChutan Formula Regulating DLL4-Notch Signaling to Inhibit Angiogenesis in Lung Cancer.BioMed research international · 2021Article
- Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice.American journal of physiology. Heart and circulatory physiology · 2020Article
- Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction.JCI insight · 2019Article
- Novel Methods for High-resolution Assessment of Cardiac Action Potential Repolarization.Biomedical signal processing and control · 2019Article
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 1 country.
Giulia BorghettiDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Carol A EisenbergDepartment of Physiology, New York Medical College, Valhalla, New York.
Sergio SignoreDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Andrea SorrentinoDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Keerat KaurDepartment of Physiology, New York Medical College, Valhalla, New York.
Alejandro Andrade-VicentyDepartment of Physiology, New York Medical College, Valhalla, New York.
John G EdwardsDepartment of Physiology, New York Medical College, Valhalla, New York.
Mriganka NerkarDepartment of Physiology, New York Medical College, Valhalla, New York.
Khaled QanudDepartment of Physiology, New York Medical College, Valhalla, New York.ORCID 0000-0003-2943-1245
Dong SunDepartment of Physiology, New York Medical College, Valhalla, New York.
Polina GoichbergDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Annarosa LeriDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Piero AnversaDepartments of Anesthesia and Medicine, and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, Massachusetts.
Leonard M EisenbergDepartment of Physiology, New York Medical College, Valhalla, New York.
Jason T JacobsonDepartment of Physiology, New York Medical College, Valhalla, New York.
Thomas H HintzeDepartment of Physiology, New York Medical College, Valhalla, New York.
Marcello RotaDepartment of Physiology, New York Medical College, Valhalla, New York.
New York Medical College · USBrigham and Women's Hospital · USWestchester Medical Center · US
Funding
Rebuilding the Failing HeartP01HL092868 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ANVERSA, PIERO · 2008 to 2013
$12.9MRepair and Angiogenesis by Stem Cells in Human HeartR37HL081737 · NHLBI · NEW YORK MEDICAL COLLEGE · PI ANVERSA, PIERO · 2005 to 2015
$6.5MStem Cells and Myocardial Aging in DogsP01AG043353 · NIA · UNIVERSITY OF ALBUQUERQUE · PI ANVERSA, PIERO · 2013 to 2015
$4.5MEstrogen and EDHF in NO DeficiencyR01HL070653 · NHLBI · NEW YORK MEDICAL COLLEGE · PI HUANG, AN · 2003 to 2017
$3.7MStem Cells in the Developing HeartR01HL091021 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ROTA, MARCELLO · 2009 to 2013
$2.4MRedefining Human Myocardial BiologyR01HL105532 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ANVERSA, PIERO, BUCHHOLZ, BRUCE A · 2011 to 2014
$2.2MImmortal DNA Strand and Cardiac Stem Cell AgingR01AG037495 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI ANVERSA, PIERO · 2011 to 2014
$2.0MTelomeric Shortening, p53 and miR-34a Condition Senescence of Cardiac ProgenitorsR01AG037490 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI LERI, ANNAROSA · 2010 to 2014
$1.7MCardiomyogenesis in the Adult HeartR01HL114346 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LERI, ANNAROSA, ROTA, MARCELLO · 2012 to 2015
$1.7MCardiac Stem Cells and AngiomyogenesisR01HL111183 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LERI, ANNAROSA · 2012 to 2015
$1.7MFerrochelatase & guanylate cyclase regulation in vascular dysfunctionR01HL129797 · NHLBI · NEW YORK MEDICAL COLLEGE · PI SUN, DONG, WOLIN, MICHAEL S · 2016 to 2019
$1.6MNHLBI NIH HHS P01 HL092868NHLBI NIH HHS R01 HL070653NHLBI NIH HHS R01 HL091021NHLBI NIH HHS R01 HL105532NHLBI NIH HHS R01 HL111183NHLBI NIH HHS R01 HL114346NHLBI NIH HHS R01 HL129797NHLBI NIH HHS R37 HL081737NIA NIH HHS P01 AG043353NIA NIH HHS R01 AG037490NIA NIH HHS R01 AG037495
Abstract
Notch receptor signaling is active during cardiac development and silenced in myocytes after birth. Conversely, outward K
Indexed as
Signal TransductionAnimalsCells, CulturedFemaleKineticsKv Channel-Interacting ProteinsMaleMembrane PotentialsMice, Inbred C57BLMice, TransgenicMyocytes, CardiacPotassiumPotassium Channels, Voltage-GatedReceptor, Notch1SodiumKcnip2 protein, mouseKv Channel-Interacting ProteinsNotch1 protein, mousePotassiumPotassium Channels, Voltage-GatedReceptor, Notch1SodiumelectrophysiologyKv currentsmyocytesNotch receptor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.