Evidence map›Paper›PMID 28939643›Full record

ArticlePhysiological genomics2017

Role of G protein-coupled receptor kinase-6 in

Taehyung Lee, Nandakumar Packiriswamy, Eunhee Lee, Peter C Lucas, Laura R McCabe, Narayanan Parameswaran

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Taehyung LeeDepartment of Physiology, Michigan State University, East Lansing, Michigan; and.
Nandakumar PackiriswamyDepartment of Physiology, Michigan State University, East Lansing, Michigan; and.
Eunhee LeeDepartment of Physiology, Michigan State University, East Lansing, Michigan; and.
Peter C LucasDepartment of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Laura R McCabeDepartment of Physiology, Michigan State University, East Lansing, Michigan; and.ORCID http://orcid.org/0000-0001-5407-162X
Narayanan ParameswaranDepartment of Physiology, Michigan State University, East Lansing, Michigan; and narap@msu.edu.ORCID http://orcid.org/0000-0002-8894-5564
Michigan State University · USUniversity of Pittsburgh · US

Funding

Mechanistic basis of probiotic prevention of osteoporosisR01AT007695 · NCCIH · MICHIGAN STATE UNIVERSITY · PI BRITTON, ROBERT A, MCCABE, LAURA R · 2013 to 2017
$2.2M
GPCR Kinase-2 in TNFalpha Signaling in MacrophagesR01HL095637 · NHLBI · MICHIGAN STATE UNIVERSITY · PI PARAMESWARAN, NARAYANAN · 2009 to 2013
$1.8M
Arrestins in TLR4 Signaling in MacrophagesR01AR056680 · NIAMS · MICHIGAN STATE UNIVERSITY · PI PARAMESWARAN, NARAYANAN · 2009 to 2013
$1.4M
The Role of the Gut and Bone Microenvironment in T1D Bone LossR01DK101050 · NIDDK · MICHIGAN STATE UNIVERSITY · PI MCCABE, LAURA R, PARAMESWARAN, NARAYANAN · 2014 to 2016
$1.1M
GPCR Kinase-5 in Inflammatory Bowel DiseaseR21AI099404 · NIAID · MICHIGAN STATE UNIVERSITY · PI PARAMESWARAN, NARAYANAN · 2013 to 2014
$397k
NCCIH NIH HHS R01 AT007695NHLBI NIH HHS R01 HL095637NIAID NIH HHS R21 AI099404NIAMS NIH HHS R01 AR056680NIDDK NIH HHS R01 DK101050
6 · The paper itself

Abstract

G protein-coupled receptor kinase-6 (GRK6) is a serine/threonine kinase that is important in inflammatory processes. In this study, we examined the role of GRK6 in

Indexed as

AnimalsApoptosisBacterial LoadBronchoalveolar Lavage FluidDisease Models, AnimalEscherichia coli InfectionsGene Expression RegulationG-Protein-Coupled Receptor KinasesInflammationLung DiseasesMice, Inbred C57BLMice, KnockoutMicrobial ViabilityNeutrophilsPhagocytosisReceptors, ChemokineG-protein-coupled receptor kinase 6G-Protein-Coupled Receptor KinasesReceptors, Chemokinebacterial infectionbronchoalveolarGRK6GRKs

Identifiers

PMID28939643
PMCPMC5792138
OpenAlexW2758609240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.