ArticleProgress in neuro-psychopharmacology & biological psychiatry2018
Neural and psychological characteristics of college students with alcoholic parents differ depending on current alcohol use.
Article in Progress in neuro-psychopharmacology & biological psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Genetic Variants Associated With Resilience in Human and Animal Studies.Frontiers in psychiatry · 2022Pooled it
- Clinical utility of pharmacogenetics in a psychiatric and primary care population.The pharmacogenomics journal · 2023Trial
- Associations between parental alcoholism and delinquent behaviours among youth: exploring serial and parallel mediation by posttraumatic stress disorder symptoms, anxiety symptoms and impulsivity.European journal of psychotraumatology · 2025Article
- Biopsychosocial Profile of Chronic Alcohol Users: Insights from a Cross-Sectional Study.Brain sciences · 2025Article
- The influence of parents' history of alcohol use on their university-going children's drinking habits: A comparative study of students' drinking habits.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025Article
- Differing Effects of Alcohol Use on Epigenetic and Brain Age in Adult Children of Parents with Alcohol Use Disorder.Brain sciences · 2024Article
- Smoking-Related Increases in Alcohol Outcomes and Preliminary Evidence for the Protective Effect of a Functional Nicotine Receptor Gene (CHRNA5) Variant on Alcohol Consumption in Individuals Without Alcohol Use Disorder.The international journal of neuropsychopharmacology · 2024Article
- The collaborative study on the genetics of alcoholism: Brain function.Genes, brain, and behavior · 2023Review
- The relevant research of adverse childhood experiences and "risky drinking" in children of alcoholics in China.BMC psychiatry · 2023Article
- Methylation of genes and regulation of inflammatory processes on emotional response in young adults with alcoholic parents.Brain, behavior, & immunity - health · 2022Article
- [Depression, anxiety and stress in college students before and during the first three months of COVID-19 lockdown].Revista colombiana de psiquiatria · 2022Article
- The Personality Traits and P300 of Offspring of Parents With Alcohol Dependence Differ Depending on Current Risky Drinking: A Preliminary Case-Control Study.Frontiers in psychiatry · 2022Article
- Resource Factors Allowing People with Alcohol-addicted Parents to Overcome Their Negative Emotions: A Latent Variable Model and Content Analysis.Psychology in Russia : state of the art · 2021Article
- Trajectories of brain development reveal times of risk and factors promoting resilience to alcohol use during adolescence.International review of neurobiology · 2021Review
- Coping Strategies and Personality Profile Characteristics of People Whose Parents Were Alcohol Addicts.Behavioral sciences (Basel, Switzerland) · 2020Article
- The effect of alcohol use on neuroimaging correlates of cognitive and emotional processing in human adolescence.Neuropsychology · 2019Review
- Functional Domains of Substance Use and their Implications to Trauma: A Systematic Review of Neuroimaging Studies.Chronic stress (Thousand Oaks, Calif.)Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
A significant proportion of college students are adult children of an alcoholic parent (ACoA), which can confer greater risk of depression, poor self-esteem, alcohol and drug problems, and greater levels of college attrition. However, some ACoA are resilient to these negative outcomes. The goal of this study was to better understand the psychobiological factors that distinguish resilient and vulnerable college-aged ACoAs. To do so, scholastic performance and psychological health were measured in ACoA college students not engaged in hazardous alcohol use (resilient) and those currently engaged in hazardous alcohol use (vulnerable). Neural activity (as measured by functional magnetic resonance imaging) in response to performing working memory and emotion-based tasks were assessed. Furthermore, the frequency of polymorphisms in candidate genes associated with substance use, risk taking and stress reactivity were compared between the two ACoA groups. College ACoAs currently engaged in hazardous alcohol use reported more anxiety, depression and posttraumatic stress symptoms, and increased risky nicotine and marijuana use as compared to ACoAs resistant to problem alcohol use. ACoA college students with current problem alcohol showed greater activity of the middle frontal gyrus and reduced activation of the posterior cingulate in response to visual working memory and emotional processing tasks, which may relate to increased anxiety and problem alcohol and drug behaviors. Furthermore, polymorphisms of cholinergic receptor and the serotonin transporter genes also appear to contribute a role in problem alcohol use in ACoAs. Overall, findings point to several important psychobiological variables that distinguish ACoAs based on their current alcohol use that may be used in the future for early intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.