Evidence map›Paper›PMID 28938689›Full record

ReviewOncotarget2017

Efficacy and safety of traditional chemotherapies for patients with ovarian neoplasm: a network meta-analysis.

Lili Yang, Gongliang Guo, Liqun Sun, Chenhao Li, Haipeng Zhang

RetractedOpen access · diamondAbstract readReviewRetracted Publication
In one paragraph

Review in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lili YangDepartment of Gynecology and Obstetrics, The First Hospital of Jilin University, Changchun, Jilin, China.
Gongliang GuoDepartment of Cardiology, China Japan Union Hospital Jilin University, Changchun, Jilin, China.
Liqun SunOutpatient Department of Pediatrics, The First Hospital of Jilin University, Changchun, Jilin, China.
Chenhao LiDepartment of Nephropathy, The First Hospital of Jilin University, Changchun, Jilin China.
Haipeng ZhangDepartment of Gynecology, The First Hospital of Jilin University, Changchun, Jilin, China.
First Hospital of Jilin University · CNJilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOvarian neoplasm is a kind of high risky cancer among female. This paper assessed the efficacy and safety of twelve therapies and figured out the superior chemotherapeutic drug for ovarian cancer through network meta-analysis (NMA).

methodEligible randomized controlled trials (RCTs) were retrieved from electronic databases. Primary outcomes concerning efficacy, overall survival (OS) and progression-free survival (PFS), were presented as hazard ratio (HR) and the associated 95% credible interval(

resultElectronic databases such as PubMed and Embase were searched to finally obtain 19 eligible studies of 16290 patients. In accordance of primary outcomes, when it came to 3-y PFS, paclitaxel/epirubicin/carboplatin (Pa/E/Ca) and pegylated liposomal doxorubicin/ paclitaxel/ carboplatin (PLD/Pa/Ca) were preferred compared to carboplatin (Ca) (HR= 0.80, 95%

conclusionPLD/Pa/Ca, PLD/Ca and Pa/E/Ca are highly recommended as potential therapeutically choices for patients with ovarian cancer. But considering the lack of safety data for PLD/Pa/Ca, this intervention should be taken with caution.

Indexed as

carboplatinnetwork meta-analysisovarian neoplasmpaclitaxelpegylated liposomal doxorubicin

Identifiers

PMID28938689
PMCPMC5601785
OpenAlexW2597995838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.