Evidence map›Paper›PMID 28938678›Full record

ArticleOncotarget2017

The response of the Oxford classification to steroid in IgA nephropathy: a systematic review and meta-analysis.

Pingping Yang, Xi Chen, Lei Zeng, Hua Hao, Gaosi Xu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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  14. Primary IgA nephropathy: current challenges and future prospects.International journal of nephrology and renovascular disease · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pingping Yang *Department of Nephrology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xi Chen *Grade 2013, The Second Clinical Medical College of Nanchang University, Nanchang, China.
Lei ZengDepartment of Pathology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Hua HaoDepartment of Pathology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Gaosi XuDepartment of Nephrology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Second Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present review is aimed to evaluate the correlation between pathological features and the response to steroid in the patients with IgA nephropathy according to the Oxford classification, mesangial hypercellularity (M), endocapillary hypercellularity (E), segmental glomerulosclerosis (S), tubular atrophy and interstitial fibrosis (T).

methodsWe searched Chinese Biomedical Database, EMBASE, Cochrane Library, PubMed and MEDLINE with all spellings of "IgA nephropathy", "Oxford Classification", and "steroid".

results5 studies with 637 patients were eligible for inclusion. The analysis showed that M1, S1, and T1/2 was strongly associated with the prediction to steroid resistance when compared with M0 [odds ratio (OR) 1.89, 95% confidence interval (

conclusionIgA nephropathy patients with serious pathological changes (M1, S1, and T1/2) were more resistant to steroid than slight ones (M0, S0, and T0), and E1 is better response to steroid therapy than T1/2.

Indexed as

IgA nephropathyOxford classificationproteinuriasteroid

Identifiers

PMID28938678
PMCPMC5601774
OpenAlexW2736780400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.