Evidence map›Paper›PMID 28938545›Full record

ArticleOncotarget2017

Overexpression of leptin receptor in human glioblastoma: Correlation with vasculogenic mimicry and poor prognosis.

Guosheng Han, Yanan Li, Yiqun Cao, Zhijian Yue, Yuhui Zhang, Laixing Wang, Jianmin Liu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Caveolin-1 promotes tumor cell proliferation and vasculogenic mimicry formation in human glioma.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Guosheng Han *Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yanan Li *Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yiqun Cao *Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Zhijian YueDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yuhui ZhangDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Laixing WangDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Jianmin LiuDepartment of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Second Military Medical University · CNChanghai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasculogenic mimicry (VM) was an important tumor blood supply to complement the endothelial cell-dependent angiogenesis, while leptin and receptor (ObR) involved in angiogenesis in glioblastoma has been reported on previous study, but the relationship between ObR expression and VM formation in human glioblastoma tissues, as well as their prognostic significance still remains unclear. In our study, we found that VM recognized by CD31-/PAS+ immunohistochemical staining in glioblastoma tissues showed a positive correlation with leptin expression (

Indexed as

glial to mesenchymal transitionglioblastomaglioblastoma stem cellsleptin receptorvasculogenic mimicry

Identifiers

PMID28938545
PMCPMC5601641
OpenAlexW2606887987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.