Evidence map›Paper›PMID 28938143›Full record

ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2017

Contribution of transcranial magnetic stimulation to assessment of brain connectivity and networks.

Mark Hallett, Riccardo Di Iorio, Paolo Maria Rossini, Jung E Park, Robert Chen, Pablo Celnik, Antonio P Strafella, Hideyuki Matsumoto, Yoshikazu Ugawa

Open access · greenAbstract readReview
In one paragraph

Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 5 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 5 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Pooled it
  2. Systematic review of repetitive transcranial magnetic stimulation for post-stroke hemiplegic shoulder pain.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
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  4. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Guideline
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  6. Trial
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  14. Repeated spaced paired-associative stimulation to the parietal-motor pathway maintains corticomotor excitability in older adults.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Mark HallettNational Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA. Electronic address: hallettm@ninds.nih.gov.
Riccardo Di IorioDepartment of Geriatrics, Institute of Neurology, Neuroscience and Orthopedics, Catholic University, Policlinic A. Gemelli Foundation, Rome, Italy.
Paolo Maria RossiniDepartment of Geriatrics, Institute of Neurology, Neuroscience and Orthopedics, Catholic University, Policlinic A. Gemelli Foundation, Rome, Italy; Brain Connectivity Laboratory, IRCCS San Raffaele Pisana, Rome, Italy.
Jung E ParkNational Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA; Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
Robert ChenKrembil Research Institute, University of Toronto, Toronto, Canada; Department of Medicine (Neurology), University of Toronto, Toronto, Canada.
Pablo CelnikDepartment of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, USA.
Antonio P StrafellaKrembil Research Institute, University of Toronto, Toronto, Canada; Morton and Gloria Shulman Movement Disorder Unit & E.J. Safra Parkinson Disease Program, Toronto Western Hospital, UHN, Canada; Research Imaging Centre, Campbell Family Mental Health Research Institute, CAMH, University of Toronto, Ontario, Canada.
Hideyuki MatsumotoDepartment of Neurology, Japanese Red Cross Medical Center, Japan.
Yoshikazu UgawaDepartment of Neurology, School of Medicine, Fukushima Medical University, Japan; Fukushima Global Medical Science Center, Advanced Clinical Research Center, Fukushima Medical University, Japan.
Agostino Gemelli University Polyclinic · ITNational Institute of Neurological Disorders and Stroke · USFukushima Medical University · JPJapanese Red Cross Medical Center · JPJohns Hopkins University · USKrembil Foundation · CAKrembil Research Institute

Funding

Physiology of Voluntary MovementZIANS002669 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI HALLETT, MARK · 2009 to 2023
$15.4M
Novel Strategies to Enhance Motor Function After StrokeR01HD053793 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CELNIK, PABLO ARIEL · 2007 to 2019
$5.2M
Understanding Motor Behavior After StrokeR01HD073147 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CELNIK, PABLO ARIEL · 2012 to 2016
$1.7M
Intramural NIH HHS ZIA NS002669NICHD NIH HHS R01 HD053793NICHD NIH HHS R01 HD073147
6 · The paper itself

Abstract

The goal of this review is to show how transcranial magnetic stimulation (TMS) techniques can make a contribution to the study of brain networks. Brain networks are fundamental in understanding how the brain operates. Effects on remote areas can be directly observed or identified after a period of stimulation, and each section of this review will discuss one method. EEG analyzed following TMS is called TMS-evoked potentials (TEPs). A conditioning TMS can influence the effect of a test TMS given over the motor cortex. A disynaptic connection can be tested also by assessing the effect of a pre-conditioning stimulus on the conditioning-test pair. Basal ganglia-cortical relationships can be assessed using electrodes placed in the process of deep brain stimulation therapy. Cerebellar-cortical relationships can be determined using TMS over the cerebellum. Remote effects of TMS on the brain can be found as well using neuroimaging, including both positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). The methods complement each other since they give different views of brain networks, and it is often valuable to use more than one technique to achieve converging evidence. The final product of this type of work is to show how information is processed and transmitted in the brain.

Indexed as

BrainHumansNerve NetNeuroimagingTranscranial Magnetic StimulationBasal gangliaBrain networkCerebellumConnectomeEEGFunctional magnetic resonance imagingPositron emission tomographyTranscranial magnetic stimulation

Identifiers

PMID28938143
PMCPMC5679437
OpenAlexW2753000164

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.