Evidence map›Paper›PMID 28938051›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2016

Pregnancy disorders in Africa and the obstetric dilemma.

Annettee Nakimuli, Ashley Moffett

Abstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Annettee NakimuliDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University College of Health Sciences, Mulago Hill Road, P.O.Box 7072, Kampala, Uganda.
Ashley MoffettDepartment of Pathology, University of Cambridge, Cambridge, UK.

Funding

NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
British Heart Foundation PG/09/077/27964FIC NIH HHS D43 TW010132Wellcome Trust
6 · The paper itself

Abstract

The high neonatal and maternal morbidity and mortality associated with the extremes of birth weight is referred to as the obstetric dilemma. Pre-eclampsia and other conditions that lead to low birth weight are considered as the Great Obstetrical Syndromes (GOS). At the other extreme is high birth weight resulting in obstructed labour. Fetal weight largely depends on placental function and defective placentation is a common feature of the GOS. There is evidence that the local uterine immune system (KIR and HLA-C) regulates placentation, with racial differences noted. These differences may be responsible for the striking obstetric dilemma in Africans.

Indexed as

Infant MortalityMaternal MortalityAcute-Phase ReactionAfrica South of the SaharaFemaleFetal Growth RetardationFetal MacrosomiaGenetic VariationHLA-C AntigensHumansInfantInfant, NewbornInfant, Small for Gestational AgeInflammationMaternal-Fetal ExchangeMaternal Nutritional Physiological PhenomenaHLA-C AntigensKIR2DL1 protein, humanKIR2DS1 protein, humanKIR2DS5 protein, humanReceptors, KIRReceptors, KIR2DL1AfricaGreat Obstetrical SyndromesKIRObstetric dilemmaPre-eclampsiaUganda

Identifiers

PMID28938051
PMCPMC5412071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.