Evidence map›Paper›PMID 28937045›Full record

ReviewChinese medical journal2017

Carotid Atherosclerosis and Cognitive Impairment in Nonstroke Patients.

Wei-Hong Chen, Wei Jin, Pei-Yuan Lyu, Yang Liu, Rui Li, Ming Hu, Xiang-Jian Xiao

Open access · greenAbstract readReview
In one paragraph

Review in Chinese medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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  12. Ischemia as a common trigger for Alzheimer's disease.Frontiers in aging neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wei-Hong ChenGraduate School, Hebei Medical University; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Wei JinDepartment of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Pei-Yuan LyuGraduate School, Hebei Medical University; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Yang LiuGraduate School, Hebei Medical University; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Rui LiGraduate School, Hebei Medical University; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Ming HuDepartment of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Xiang-Jian XiaoDepartment of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Hebei General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAs a vascular risk factor, carotid atherosclerosis is crucial to cognitive impairment. While carotid intima-media thickness, carotid artery plaque, and carotid stenosis can reflect carotid atherosclerosis in different stages, this review aimed to explore researches on the role of carotid intima-media thickness, carotid artery plaque, and carotid stenosis in the progress of cognitive impairment in nonstroke patients and tried to illustrate the possible mechanisms. DATA SOURCES: We searched the PubMed database for recently published research articles up to July 2017, with the key words of "carotid atherosclerosis," "carotid intima-media thickness," "carotid plaque," "carotid stenosis," "nonstroke," and "cognitive impairment." STUDY SELECTION: Articles were obtained and reviewed to analyze the role of carotid atherosclerosis such as carotid intima-thickness, carotid plaque, and carotid stenosis in the progress of cognitive impairment in nonstroke patients and the possible mechanisms.

resultsIn recent years, most studies proved that by evaluating carotid atherosclerosis with ultrasonography, carotid atherosclerosis accounts for the development of cognitive decline in nonstroke patients. Carotid atherosclerosis not only impairs the subtle general cognitive function but also decreases the specific domains of cognitive function, such as memory, motor function, visual perception, attention, and executive function. But, it is still controversial. The possible mechanisms of cognitive impairment in nonstroke patients with carotid atherosclerosis can be classified as systemic global cerebrovascular function, small-vessel diseases, and the mixed lesions.

conclusionsCarotid atherosclerosis can be used to predict the risk of cognitive impairment. Furthermore, diagnosing and treating carotid atherosclerosis at early stage might help clinicians prevent and treat vascular cognitive impairment in nonstroke patients.

Indexed as

Carotid Artery DiseasesCarotid Intima-Media ThicknessCarotid StenosisCognitionCognitive DysfunctionFemaleHumansMale

Identifiers

PMID28937045
PMCPMC5634090
OpenAlexW2985973010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.