Failure of optimized dual proton pump inhibitor amoxicillin therapy: What now?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Vonoprazan-amoxicillin dual therapy forSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
   Pooled it
2. First-Line Levofloxacin-Based Triple Therapy Versus Standard Bismuth-Based Quadruple Therapy forHealth science reports · 2025
   Article
3. High-dose dual therapyTherapeutic advances in gastroenterology · 2023
   Article
4. Current guidelines forWorld journal of clinical cases · 2022
   Review
5. Probiotics as the live microscopic fighters against Helicobacter pylori gastric infections.BMC gastroenterology · 2021
   Article
6. Therapeutic advances in gastroenterology · 2021
   Review
7. Predictors of triple therapy treatment failure among H. pylori infected patients attending at a tertiary hospital in Northwest Tanzania: a prospective study.BMC infectious diseases · 2019
   Article
8. Relative potency of proton-pump inhibitors, Helicobacter pylori therapy cure rates, and meaning of double-dose PPI.Helicobacter · 2019
   Article
9. Role of Probiotics inThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019
   Article
10. Current and Future Treatment of Helicobacter pylori Infections.Advances in experimental medicine and biology · 2019
    Review
11. Understanding treatment guidelines with bismuth and non-bismuth quadruple Helicobacter pylori eradication therapies.Expert review of anti-infective therapy · 2018
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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