Evidence map›Paper›PMID 28936761›Full record

ReviewNeuroscience bulletin2017

Biomarkers for Parkinson's Disease: Recent Advancement.

Sharvari Lotankar, Kedar S Prabhavalkar, Lokesh K Bhatt

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Neuroscience bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 136 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03848455 completednot on this mapstarted 2019, after this paper: background citation

Multi-chip Meta-analysis of Parkinson's Disease for Clinical Validation of Small Samples of Key Genes in Disease

TypeobservationalSponsorZhujiang HospitalRan2019 to 2021Enrolled238ConditionsParkinson's DiseaseArmsgenetic diagnosis
NCT05621642 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Telerehabilitation-Based Exercise Training on Breathing, Balance and Gait Parameters in Parkinson's Patients

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled40ConditionsParkinson Disease, Respiration, Gait Disorders, NeurologicArmsBreathing exercises, Core stabilization exercises, Balance and strengthening exercises
3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 2 syntheses or guidelines pooled it, 274 citations in OpenAlex.

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76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sharvari LotankarDepartment of Pharmacology, SVKM's Dr Bhanuben Nanavati College of Pharmacy, Vile Parle (W), Mumbai, India.
Kedar S PrabhavalkarDepartment of Pharmacology, SVKM's Dr Bhanuben Nanavati College of Pharmacy, Vile Parle (W), Mumbai, India. kspharmac@gmail.com.
Lokesh K BhattDepartment of Pharmacology, SVKM's Dr Bhanuben Nanavati College of Pharmacy, Vile Parle (W), Mumbai, India.
Shri Vile Parle Kelavani Mandal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a multi-factorial degenerative disease, Parkinson's disease (PD) leads to tremor, gait rigidity, and hypokinesia, thus hampering normal living. As this disease is usually detected in the later stages when neurons have degenerated completely, cure is on hold, ultimately leading to death due to the lack of early diagnostic techniques. Thus, biomarkers are required to detect the disease in the early stages when prevention is possible. Various biomarkers providing early diagnosis of the disease include those of imaging, cerebrospinal fluid, oxidative stress, neuroprotection, and inflammation. Also, biomarkers, alone or in combination, are used in the diagnosis and evolution of PD. This review encompasses various biomarkers available for PD and discusses recent advances in their development.

Indexed as

BiomarkersComorbidityHumansNeuroimagingParkinson DiseaseBiomarkersBiochemical biomarkersClinical biomarkersGenetic biomarkersImaging biomarkersParkinson’s disease

Identifiers

PMID28936761
PMCPMC5636742
OpenAlexW2759570583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.