Evidence map›Paper›PMID 28936703›Full record

SynthesisEuropean journal of applied physiology2017

Cross-education of muscular strength following unilateral resistance training: a meta-analysis.

A Manca, D Dragone, Z Dvir, Franca Deriu

Registry-linked trialAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03511469 (Effects of Kontralateral Training in Patients With Bankart Lesion), which is not on this map. Cited by 72 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03511469 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of Kontralateral Training in Patients With Bankart Lesion

TypeinterventionalSponsorHacettepe UniversityRan2019 to 2021Enrolled30ConditionsStrenght of Rotator Cuff MusclesArmsControl Group, Isokinetic Group
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  13. Cross education is modulated by set configuration in knee extension exercise.Journal of musculoskeletal & neuronal interactions · 2023
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  19. Cross-education improves quadriceps strength recovery after ACL reconstruction: a randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A MancaDepartment of Biomedical Sciences, University of Sassari, Viale S. Pietro 43/b, 07100, Sassari, Italy.
D DragoneDepartment of Biomedical Sciences, University of Sassari, Viale S. Pietro 43/b, 07100, Sassari, Italy.
Z DvirDepartment of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Franca DeriuDepartment of Biomedical Sciences, University of Sassari, Viale S. Pietro 43/b, 07100, Sassari, Italy. deriuf@uniss.it.ORCID http://orcid.org/0000-0001-8235-6091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCross-education (CE) of strength is a well-known phenomenon whereby exercise of one limb can induce strength gains in the contralateral untrained limb. The only available meta-analyses on CE, which date back to a decade ago, estimated a modest 7.8% increase in contralateral strength following unilateral training. However, in recent years new evidences have outlined larger contralateral gains, which deserve to be systematically evaluated. Therefore, the aim of this meta-analysis was to appraise current data on CE and determine its overall magnitude of effect.

methodsFive databases were searched from inception to December 2016. All randomized controlled trials focusing on unilateral resistance training were carefully checked by two reviewers who also assessed the eligibility of the identified trials and extracted data independently. The risk of bias was assessed using the Cochrane Risk-of-Bias tool.

resultsThirty-one studies entered the meta-analysis. Data from 785 subjects were pooled and subgroup analyses by body region (upper/lower limb) and type of training (isometric/concentric/eccentric/isotonic-dynamic) were performed. The pooled estimate of CE was a significant 11.9% contralateral increase (95% CI 9.1-14.8; p < 0.00001; upper limb: + 9.4%, p < 0.00001; lower limb: + 16.4%, p < 0.00001). Significant CE effects were induced by isometric (8.2%; p = 0.0003), concentric (11.3%; p < 0.00001), eccentric (17.7%; p = 0.003) and isotonic-dynamic training (15.9%; p < 0.00001), although a high risk of bias was detected across the studies.

conclusionsUnilateral resistance training induces significant contraction type-dependent gains in the contralateral untrained limb. Methodological issues in the included studies are outlined to provide guidance for a reliable quantification of CE in future studies.

Indexed as

Muscle StrengthHumansMuscle, SkeletalRandomized Controlled Trials as TopicResistance TrainingContralateral trainingMeta-analysisResistance trainingStrength

Identifiers

PMID28936703

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.