ArticleEuropean journal of nuclear medicine and molecular imaging2018
Texture analysis of high-resolution dedicated breast
Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- PET-Derived Radiomics and Artificial Intelligence in Breast Cancer: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.Scientific reports · 2020Trial
- Association ofMolecular imaging and radionuclide therapy · 2026Article
- Novel 4D radiomics applied to dynamic FES PET images to improve prediction of breast cancer response to ER-targeted therapy.European journal of nuclear medicine and molecular imaging · 2026Article
- Relationship Between [European journal of breast health · 2025Article
- Importance of 18F-fluorodeoxyglucose positron emission tomography/computed tomography heterogeneity indices in non-small cell lung cancer.Revista da Associacao Medica Brasileira (1992) · 2025Article
- FAST (fast analytical simulator of tracer)-PET: an accurate and efficient PET analytical simulation tool.Physics in medicine and biology · 2024Article
- Respective contribution of baseline clinical data, tumour metabolism and tumour blood-flow in predicting pCR after neoadjuvant chemotherapy in HER2 and Triple Negative breast cancer.EJNMMI research · 2024Article
- Article
- Assessing dynamic metabolic heterogeneity in non-small cell lung cancer patients via ultra-high sensitivity total-body [European journal of nuclear medicine and molecular imaging · 2022Article
- Radiomics in Oncological PET Imaging: A Systematic Review-Part 1, Supradiaphragmatic Cancers.Diagnostics (Basel, Switzerland) · 2022Review
- Can Radiomics Analyses inMolecular imaging and radionuclide therapy · 2022Article
- Article
- Frontiers and hotspots ofFrontiers in oncology · 2022Article
- Is FDG-PET texture analysis related to intratumor biological heterogeneity in lung cancer?European radiology · 2021Article
- Application-specific nuclear medicalPhysics in medicine and biology · 2021Review
- A Systematic Review of PET Textural Analysis and Radiomics in Cancer.Diagnostics (Basel, Switzerland) · 2021Review
- Single-Photon Emission Computed Tomography/Computed Tomography Image-Based Radiomics for Discriminating Vertebral Bone Metastases From Benign Bone Lesions in Patients With Tumors.Frontiers in medicine · 2021Article
- Biological correlates of tumor perfusion and its heterogeneity in newly diagnosed breast cancer using dynamic first-passEuropean journal of nuclear medicine and molecular imaging · 2020Article
- Progress and Future Trends in PET/CT and PET/MRI Molecular Imaging Approaches for Breast Cancer.Frontiers in oncology · 2020Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
purposeThis study aims to determine whether PET textural features measured with a new dedicated breast PET scanner reflect biological characteristics of breast tumors.
methodsOne hundred and thirty-nine breast tumors from 127 consecutive patients were included in this analysis. All of them underwent a
resultsAlong with well-established associations, new correlations were found. HER2-positive tumors had significantly higher uptake (p < 0.001, AUCs > 0.70) and presented different global and regional heterogeneity (p = 0.002, p = 0.016, respectively, AUCs < 0.70). Nine out of ten analyzed features were significantly associated with immunohistochemical subtype. Uptake was lower for LA tumors (p < 0.001) with AUCs ranging from 0.71 to 0.88 for each subgroup comparison. Heterogeneity metrics were significantly associated when comparing LA and LB - (p < 0.01), being regional heterogeneity metrics more discriminative than any other parameter (AUC = 0.80 compared to AUC = 0.71 for SUV). LB+ and HER2pnl tumors also showed more regional heterogeneity than LA tumors (AUCs = 0.79 and 0.84, respectively). After comparison with whole-body PET studies, we observed an overall improvement in the classification ability of both non-heterogeneity metrics and textural features.
conclusionsPET parameters extracted from high-resolution dedicated breast PET images showed new and stronger correlations with immunohistochemical factors and immunohistochemical subtype of breast cancer compared to whole-body PET.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.