Evidence map›Paper›PMID 28936489›Full record

ArticleMedical computer vision and Bayesian and graphical models for biomedical imaging : MICCAI 2016 international workshop, MCV and BAMBI, Athens, Greece, October 21, 2016 : revised selected papers2016

Landmark-Based Alzheimer's Disease Diagnosis Using Longitudinal Structural MR Images.

Jun Zhang, Mingxia Liu, Le An, Yaozong Gao, Dinggang Shen

Abstract read
In one paragraph

Article in Medical computer vision and Bayesian and graphical models for biomedical imaging : MICCAI 2016 international workshop, MCV and BAMBI, Athens, Greece, October 21, 2016 : revised selected papers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun ZhangDepartment of Radiology and BRIC, UNC at Chapel Hill, Chapel Hill, NC, USA.
Mingxia LiuDepartment of Radiology and BRIC, UNC at Chapel Hill, Chapel Hill, NC, USA.
Le AnDepartment of Radiology and BRIC, UNC at Chapel Hill, Chapel Hill, NC, USA.
Yaozong GaoDepartment of Radiology and BRIC, UNC at Chapel Hill, Chapel Hill, NC, USA.
Dinggang ShenDepartment of Radiology and BRIC, UNC at Chapel Hill, Chapel Hill, NC, USA.

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Analyzing Large-Scale Neuroimaging Data in Alzheimer's DiseaseRF1AG053867 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2016
$2.5M
NIA NIH HHS RF1 AG053867NIBIB NIH HHS R01 EB008374
6 · The paper itself

Abstract

In this paper, we propose a landmark-based feature extraction method for AD diagnosis using longitudinal structural MR images, which requires no nonlinear registration or tissue segmentation in the application stage and is robust to the inconsistency among longitudinal scans. Specifically, (1) the discriminative landmarks are first automatically discovered from the whole brain, which can be efficiently localized using a fast landmark detection method for the testing images; (2) High-level statistical spatial features and contextual longitudinal features are then extracted based on those detected landmarks. Using the spatial and longitudinal features, a linear support vector machine (SVM) is adopted for distinguishing AD subjects from healthy controls (HCs) and also mild cognitive impairment (MCI) subjects from HCs, respectively. Experimental results demonstrate the competitive classification accuracies, as well as a promising computational efficiency.

Identifiers

PMID28936489
PMCPMC5603322

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.