Clinical Characteristics of Non-Melanoma Skin Cancers Recurring within 5 years after Mohs Micrographic Surgery: Single Institution Retrospective Chart Review.

Tina Vajdi, Robert Eilers, Shang I Brian Jiang

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Article in Journal of clinical and investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Tina VajdiDepartment of Dermatology, School of Medicine, University of California , San Diego, CA, USA.

Robert EilersDepartment of Dermatology, Dermatologic and Mohs Micrographic Surgery Center, School of Medicine, University of California San Diego, CA, USA.

Shang I Brian JiangDepartment of Dermatology, Dermatologic and Mohs Micrographic Surgery Center, School of Medicine, University of California San Diego, CA, USA.

Funding

T35 Short Term Research Training GrantT35HL007491 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAVOIA, MARIA CHRISTINA · 1985 to 2015

$2.8M

NHLBI NIH HHS T35 HL007491

6 · The paper itself

Abstract

backgroundMohs micrographic surgery (MMS) is used to treat certain high-risk non-melanoma skin cancers (NMSC) due to its high cure rate. However, clinical recurrences do occur in a small number of cases.

objectiveWe examined specific clinical characteristics associated with NMSC recurrences following MMS.

methodsWe employed a retrospective chart review of the 1467 cases of NMSC that underwent MMS at UC San Diego from January 1, 2008 through December 31, 2009. A total of 356 cases were excluded due to lack of follow-up.

resultsFive (0.45%) of 1111 cases developed recurrences of NMSC at the site of MMS. There were 741 cases of basal cell carcinomas (BCC); 3 were recurrences (0.40%). There were 366 cases of squamous cell carcinomas (SCC); 2 were recurrences (0.55%). Review of MMS histopathology of these recurrent tumors showed that there were no errors or difficulty with the processing or interpretation of the slides.

conclusionFive-year recurrence rate of NMSC following MMS at our institution is below the reported average. Our retrospective chart review identified specific clinical characteristics associated with NMSC recurrence including a history of smoking, anatomical location on the cheeks, ears or nose, and a history of immunosuppression for SCCs.

Identifiers

PMID28936477

DOI10.13188/2373-1044.1000036

PMCPMC5603292

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