ReviewJournal of clinical and experimental dentistry2017
Oral lymphoepithelial cyst: A clinicopathological study of 26 cases and review of the literature.
Review in Journal of clinical and experimental dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Lymphoepithelial Cyst Presenting as a Lateral Neck Mass: A Diagnostic Pitfall in Adults.Cureus · 2026Article
- Lymphoepithelial Cyst "En Crypto": A Case Report of a Rare Localization in the Superior Pole of the Palatine Tonsil.Reports (MDPI) · 2025Article
- Oral lymphoepithelial cyst at the lateral border of the tongue.Journal of dental sciences · 2023Article
- Clinical features and management of lymphoepithelial cyst.Open medicine (Warsaw, Poland) · 2023Article
- Oral Lymphoepithelial Cyst: A Collaborative Clinicopathologic Study of 132 Cases from Brazil.Head and neck pathology · 2022Article
- Unusual Site for a White Nodule on the Palatine Tonsil: Presentation, Differential Diagnosis, and Discussion.Case reports in dentistry · 2021Article
- Case of a Large Oropharyngeal Cyst.Cureus · 2019Article
- Oral lymphoid lesions: a 47-year clinicopathological study in a Brazilian population.Medical molecular morphology · 2019Review
- Lymphoepithelial cyst of the tongue.Journal of dental sciences · 2019Article
- A Guide to Yellow Oral Mucosal Entities: Etiology and Pathology.Head and neck pathology · 2019Review
- Incidental finding of subgemmal neurogenous plaque upon retrospective evaluation of oral lymphoepithelial cysts.Oral and maxillofacial surgery · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
introductionΤo describe the clinicopathological features of 26 oral lymphoepithelial cysts (LECs) and review the literature. MATERIAL AND
methodsTwenty-six cases of oral LECs diagnosed during a 37-year period were retrospectively collected. The patients' gender and age, as well as the main clinical features of the cysts were retrieved from the requisition forms. The main microscopic features were recorded after reevaluation of all cases. Pubmed and Google Scholar electronic databases were searched with the key word "oral LEC". Inclusion criteria were the microscopic confirmation of LEC diagnosis and the report at least two of three main clinical features (gender, age and cyst's location).
resultsThe 26 oral LECs represented 0.08% of 31,564 biopsies accessioned during the study period. They affected 25 patients, 14 females and 11 males with a mean age of 33.04±9.81 years. They appeared as smooth (92%) nodules, with soft (24%) or firm (76%) consistency and normal (28%), yellow to normal (20%), yellow (32%) or white (20%) hue, in the tongue (69.23%) or the floor of mouth (30.77%). They were covered by parakeratinized squamous (92.31%) or non-keratinized (7.69%) epithelium and contained desquamated epithelial cells, amorphous eosinophilic material and/or inflammatory cells (100%). The lymphoid tissue surrounded the cystic cavity partially (34.62%) or completely (65.38%), often in a follicular pattern with prominent germinal centers (53.85%). Literature review yielded 316 cases of oral LECs derived from 25 case reports, 3 case studies/retrospective studies with detailed information for each case and 7 studies with summarized data.
conclusionsOral LEC is a pathologic entity with discrete clinical presentation that is, however, commonly misdiagnosed in clinical practice as other, mostly benign, entities. Its pathogenesis remains obscure, as its clinicopathologic features are consistent with both theories suggested up to date.
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