Evidence map›Paper›PMID 28936214›Full record

ArticleFrontiers in immunology2017

A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15.

Borja Ocón, Junliang Pan, Theresa Thu Dinh, Wenjing Chen, Romain Ballet, Michael Bscheider, Aida Habtezion, Hua Tu, Brian A Zabel, Eugene C Butcher

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. GPR15-guided CD8Nature · 2026
    Article
  3. Article
  4. Review
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  6. Review
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  13. Risk of Alzheimer's disease in Down syndrome: Insights gained by multi-omics.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Borja OcónThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Junliang PanThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Theresa Thu DinhThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Wenjing ChenLake Pharma, Inc., Belmont, CA, United States.
Romain BalletThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Michael BscheiderThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Aida HabtezionDivision of Gastroenterology and Hepatology, School of Medicine, Stanford University, Stanford, CA, United States.
Hua TuLake Pharma, Inc., Belmont, CA, United States.
Brian A ZabelThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Eugene C ButcherThe Center for Molecular Biology and Medicine, Veterans Affairs Palo Alto Health Care System and The Palo Alto Veterans Institute for Research, Palo Alto, CA, United States.
Palo Alto Veterans Institute for Research · USStanford University · USLakePharma (United States) · US

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Intestinal Lymphocyte TraffickingR37AI047822 · NIAID · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI BUTCHER, EUGENE C · 2011 to 2020
$3.5M
Role and Regulation of colon Trafficking Novel G-Protein Coupled ReceptorsR01DK101119 · NIDDK · STANFORD UNIVERSITY · PI HABTEZION, AIDA · 2016 to 2019
$2.0M
Novel Mucosa-homing Dendritic Cell: Development, Trafficking and FunctionR01AI093981 · NIAID · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI BUTCHER, EUGENE C · 2012 to 2016
$1.8M
ENDOTHELIAL CELL BIOLOGY IN INFLAMMATIONR01GM037734 · NIGMS · STANFORD UNIVERSITY · PI BUTCHER, EUGENE C · 1987 to 2017
$938k
Lymphocyte Homing Mechanisms in Normal & Inflamed ColonK08DK069385 · NIDDK · STANFORD UNIVERSITY · PI HABTEZION, AIDA · 2006 to 2010
$714k
Trafficking mechanisms of locally generated colon antigen reactive T cellsR03DK085426 · NIDDK · STANFORD UNIVERSITY · PI HABTEZION, AIDA · 2010 to 2011
$143k
NHLBI NIH HHS T32 HL098049NIAID NIH HHS R01 AI093981NIAID NIH HHS R37 AI047822NIDDK NIH HHS K08 DK069385NIDDK NIH HHS R01 DK101119NIDDK NIH HHS R03 DK085426NIGMS NIH HHS R01 GM037734
6 · The paper itself

Abstract

Chemoattractants control lymphocyte recruitment from the blood, contributing to the systemic organization of the immune system. The G protein-linked receptor GPR15 mediates lymphocyte homing to the large intestines and skin. Here we show that the 9 kDa CC-motif containing cationic polypeptide AP57/colon-derived sushi containing domain-2 binding factor (CSBF), encoded by

Indexed as

chemokinecolonGPR15ligandskinT cellstrafficking receptor

Identifiers

PMID28936214
PMCPMC5594226
OpenAlexW2750710572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.