Evidence map›Paper›PMID 28936163›Full record

ArticleFrontiers in molecular neuroscience2017

Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in

Feng-Juan Gao, Sheng-Hai Zhang, Ping Xu, Bo-Qi Yang, Rong Zhang, Yun Cheng, Xu-Jiao Zhou, Wan-Jing Huang, Min Wang, Jun-Yi Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
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  3. Article
  4. Review
  5. Review
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  8. Review
  9. Article
  10. Neoteric Role of Quercetin in Visual Disorders.Current drug research reviews · 2024
    Review
  11. Review
  12. Article
  13. Glymphatic imaging and modulation of the optic nerve.Neural regeneration research · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Feng-Juan GaoEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Sheng-Hai ZhangEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Ping XuEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Bo-Qi YangEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Rong ZhangEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Yun ChengEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Xu-Jiao ZhouEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Wan-Jing HuangEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Min WangEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Jun-Yi ChenEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Xing-Huai SunEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Ji-Hong WuEye Institute, Eye and ENT Hospital, College of Medicine, Fudan UniversityShanghai, China.
Eye & ENT Hospital of Fudan University · CNScience and Technology Commission of Shanghai Municipality · CNState Key Laboratory of Medical Neurobiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is a progressive neuropathy characterized by the loss of retinal ganglion cells (RGCs). Strategies that delay or halt RGC loss have been recognized as potentially beneficial for rescuing vision in glaucoma patients. Quercetin (Qcn) is a natural and important dietary flavonoid compound, widely distributed in fruits and vegetables. Mounting evidence suggests that Qcn has numerous neuroprotective effects. However, whether Qcn exerts neuroprotective effects on RGC in glaucoma is poorly understood. In this study, we investigated the protective effect of Qcn against RGC damage in a rat chronic ocular hypertension (COHT) model

Indexed as

apoptosisglaucomamitochondrianeuroprotectionquercetinretinal ganglion cells

Identifiers

PMID28936163
PMCPMC5594060
OpenAlexW2752347620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.