Evidence map›Paper›PMID 28936129›Full record

ArticleClinical reviews in bone and mineral metabolism2016

Bone quality assessment techniques: geometric, compositional, and mechanical characterization from macroscale to nanoscale.

Heather B Hunt, Eve Donnelly

Abstract read
In one paragraph

Article in Clinical reviews in bone and mineral metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. [Research progress on enhancing osseointegration properties of polyetheretherketone implants through various modification methods].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Bone quality in endocrine diseases: determinants and clinical relevance.Journal of endocrinological investigation · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Assessing the Elasticity of Child Cortical Bone.Advances in experimental medicine and biology · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Heather B HuntDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY.
Eve DonnellyDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY.

Funding

Nonenzymatic glycation, bone quality, and microdamage in type 2 diabetic boneK01AR064314 · NIAMS · CORNELL UNIVERSITY · PI DONNELLY, EVE · 2013 to 2017
$659k
NIAMS NIH HHS K01 AR064314
6 · The paper itself

Abstract

This review presents an overview of the characterization techniques available to experimentally evaluate bone quality, defined as the geometric and material factors that contribute to fracture resistance independently of areal bone mineral density (aBMD) assessed by dual energy x-ray absorptiometry. The methods available for characterization of the geometric, compositional, and mechanical properties of bone across multiple length scales are summarized, along with their outcomes and their advantages and disadvantages. Examples of how each technique is used are discussed, as well as practical concerns such as sample preparation and whether or not each testing method is destructive. Techniques that can be used

Indexed as

computed tomographyelectron microscopyFourier transform infrared imagingmechanical testingmicroindentationnanoindentationone qualityRaman imagingreference point indentationvibrational spectroscopy

Identifiers

PMID28936129
PMCPMC5604329

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.