ArticleJournal of neurosciences in rural practice2017
High Frequency of Depressive Symptoms among Adults with Epilepsy: Results from a Hospital-based Study.
Article in Journal of neurosciences in rural practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia.Epilepsia open · 2026Article
- Review
- Systematic Literature Review of Psychiatric Comorbidities in Adults with Epilepsy.Journal of clinical neurology (Seoul, Korea) · 2021Review
- Depressive Symptoms and Health-Related Quality of Life in Patients with Cardiovascular Diseases Attending a Tertiary Care Hospital, Puducherry-A Cross-Sectional Study.Journal of neurosciences in rural practice · 2021Article
- Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study.PloS one · 2020Article
- Epilepsy and Depression: A Bidirectional Relationship.Journal of neurosciences in rural practice · 2017Article
- Depressive Symptoms in Persons with Epilepsy: Methodological Issues.Journal of neurosciences in rural practice · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextAssessment of comorbid burden of depression and associated factors among adult people living with epilepsy (PWE) has the potential to inform clinical evaluation and management to improve outcomes.
aimThe aim of this study is to determine frequency of depressive symptoms and factors associated with it among PWE attending a tertiary care hospital. SETTING AND
designThis was a cross-sectional observational study conducted in the outpatient clinic of a tertiary care center. SUBJECTS AND
methodsOne hundred and fifty patients with epilepsy were recruited between May 2016 and August 2016. For assessing depression, Tamil validated version of Patient Health Questionnaire-12 was used. Frequency of depression and its association with various sociodemographic and clinical factors were assessed. STATISTICAL ANALYSIS USED: Student
resultsOf the 150 subjects, 89 (59.3%) were males. Generalized tonic-clonic seizures were present in 131 people (87.3%). Genetic and unknown epilepsies contributed higher proportion (44.7%) as compared to structural epilepsies (37.3%). Majority (88%) were on one or two antiepileptic drugs. Thirty-one people (20.3%) had less than one seizure per year. Depressive symptoms were present in 95 patients (63.3%). In multivariate regression analysis, secondary generalized seizures and seizure frequency >1/month emerged as significant predictors of depression ([OR]: 5.48 [95% (CI): 1.35-22.28] and OR: 2.53 [95% CI: 1.11-5.75], respectively).
conclusionDepression is prevalent in a majority of adult PWE. Hence, a routine screening for depression as part of comprehensive epilepsy care is advisable for PWE attending the outpatient clinic.
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