ArticleMiddle East African journal of ophthalmology
Comparative Evaluation of Corneal Endothelium in Patients with Diabetes Undergoing Phacoemulsification.
Article in Middle East African journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients.BMC ophthalmology · 2023Pooled it
- Comparison of endothelial cell loss in diabetic patients after conventional phacoemulsification and femtosecond laser-assisted cataract surgery.BMC ophthalmology · 2023Trial
- Impact of Well-Controlled Type 2 Diabetes on Corneal Endothelium Following Cataract Surgery: A Prospective Longitudinal Analysis.Journal of clinical medicine · 2025Article
- Corneal endothelial cells and acoustic cavitation in phacoemulsification.World journal of clinical cases · 2023Review
- The Association Between Glycaemic Control, Renal Function and Post-operative Ophthalmic Complications in People With Diabetes Undergoing Cataract Surgery-A Single-Centre Retrospective Analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022Article
- Comparison of corneal endothelial changes following phacoemulsification in diabetic and non-diabetic patients.Indian journal of ophthalmology · 2022Observational
- Specular Microscopic Corneal Endothelial Cell Changes following Uneventful Phacoemulsification in Patients with Gout.Journal of ophthalmology · 2022Article
- Effect of SOX2 Repression on Corneal Endothelial Cells.International journal of molecular sciences · 2020Article
- Corneal endothelial cell changes in diabetics versus age group matched nondiabetics after manual small incision cataract surgery.Indian journal of ophthalmology · 2020Observational
- Commentary: Corneal endothelial cell changes in diabetics versus age-group matched nondiabetics after manual small incision cataract surgery (SICS).Indian journal of ophthalmology · 2020Article
- New ex vivo model of corneal endothelial phacoemulsification injury and rescue therapy with mesenchymal stromal cell secretome.Journal of cataract and refractive surgery · 2019Article
- Corneal alteration and pathogenesis in diabetes mellitus.International journal of ophthalmology · 2019Review
- Changes in the Density of Corneal Endothelial Cells in Elderly Diabetic Patients After Combined Phacovitrectomy and Ex-PRESS Glaucoma Implants.Current pharmaceutical biotechnology · 2019Article
- Effect of Reformation of the Anterior Chamber by Air or by a Balanced Salt Solution (BSS) on Corneal Endothelium after Phacoemulsification: A Comparative Study.Journal of ophthalmology · 2018Article
- Risk factors for endothelial cell damage in diabetics after phacoemulsification.Oman journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to determine if phacoemulsification with posterior chamber foldable intraocular lens implantation has a greater impact on the corneal endothelium of type 2 diabetic patients as compared to nondiabetic controls. MATERIALS AND
methodsThis study compared the corneal endothelial status in sixty patients with diabetes with good glycemic control and sixty nondiabetic controls before and after (1 week, 1 month, 2 month, and 3 month) uneventful phacoemulsification. Central corneal endothelial cell density, percentage hexagonality, and coefficient of variation were measured using a noncontact specular microscope. Central corneal thickness was taken as a surrogate marker for endothelium functional status.
resultsData were age and sex matched. Patients with diabetes showed significantly higher loss in endothelial cell count as compared to nondiabetic controls. Furthermore, the patients with diabetes showed a slower recovery trend in the endothelial healing response as evidenced by lower change in the coefficient of variation. Significant correlation was found between energy used and change in endothelial count as well as coefficient of variation in nondiabetics only.
conclusionIn spite of good glycemic control, patients with diabetes have significantly more endothelial damage in comparison to nondiabetic controls with similar nuclear grading and phaco energy used. This warrants a more careful use of phaco energy in patient with diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.