ArticleJournal of Indian Prosthodontic Society
The potential of mangosteen (
Article in Journal of Indian Prosthodontic Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 47 citations in OpenAlex.
- Osteogenic, antiresorptive, and toxicological evaluation of alpha-mangostin in MC3T3-E1 cells and medaka fish.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026Article
- The key role of RANKL and OPG as molecular biomarkers in bone remodeling associated with different grafts regarding socket preservation: A systematic review.Journal of Taibah University Medical Sciences · 2026Review
- Clinical trial landscape for guided bone regeneration: trend analysis and future perspectives.Frontiers in dental medicine · 2025Article
- Formulation of 1% α-mangostin in orabase gel induces apoptosis in oral squamous cell carcinoma.BMC complementary medicine and therapies · 2024Article
- α-Mangostin and lawsone methyl ether in tooth gel synergistically increase its antimicrobial and antibiofilm formation effects in vitro.BMC oral health · 2023Article
- Antioxidant Materials in Oral and Maxillofacial Tissue Regeneration: A Narrative Review of the Literature.Antioxidants (Basel, Switzerland) · 2023Review
- Nano-emulsion of mangosteen rind extract in a mucoadhesive patch for periodontitis regenerative treatment: An in vivo study.Journal of Taibah University Medical Sciences · 2022Article
- Mucoadhesive film containing α-mangostin shows potential role in oral cancer treatment.BMC oral health · 2021Article
- Mineralization of Phosphorylated Fish Skin Collagen/Mangosteen Scaffolds as Potential Materials for Bone Tissue Regeneration.Molecules (Basel, Switzerland) · 2021Article
- Immunohistochemical analysis of stem cells from human exfoliated deciduous teeth seeded in carbonate apatite scaffold for the alveolar bone defect in Wistar rats (F1000Research · 2020Article
- Chitosan oligosaccharide inhibits skull resorption induced by lipopolysaccharides in mice.BMC oral health · 2019Article
- Article
- Effect of α-Mangostin on Interleukin-11 and Runt-related Transcription Factor-2 Gene Expression on Cell Line Osteoblast Cultures Induced with Lipopolysaccharide.Contemporary clinical dentistryArticle
- Socket preservation with demineralized freeze-dried bone allograft and platelet-rich fibrin for implant site development: A randomized controlled trial.Journal of Indian Prosthodontic SocietyArticle
- Propolis extract and bovine bone graft combination in the expression of VEGF and FGF2 on the preservation of post extraction socket.Journal of Indian Prosthodontic SocietyArticle
- Antimicrobial and Anti-inflammatory Effects of α-Mangostin Soluble Film.Journal of International Society of Preventive & Community DentistryArticle
- Evaluation of the effect of moringa oleifera gel and autologo platelet-rich fibrin in the treatment of rabbit intra bony defects. (Radio graphic and Histological study).Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFollowing the extraction of a tooth, bone resorption can cause significant problems for a subsequent denture implant and restorative dentistry. Thus, the tooth extraction socket needs to be maintained to reduce the chance of any alveolar ridge bone resorption.
objectiveThe objective of this study is to determine whether the administration of mangosteen peel extracts (MPEs), combined with demineralized freeze-dried bovine bone xenograft (DFBBX) materials for tooth extraction socket preservation, could potentially reduce inflammation by decreased the expression of nuclear factor κβ (NfKb) and receptor activator of nuclear factor-κβ ligand (RANKL), to inhibit alveolar bone resorption, and increased of bone morphogenetic protein-2 (BMP2) expressions to accelerate alveolar bone regeneration. MATERIALS AND
methodsThis study consists of several stages. First, a dosage of MPE combined with graft materials was applied to a preserved tooth extraction socket of a
resultsThe results of this research were that it was determined that MPEs combined with graft materials on a preserved tooth extraction socket can reduce NfKb, RANK, and osteoclasts also increase of BMP2 and osteoblast.
conclusionThe induction of MPEs and DFBBX is effective in reducing inflammation, lowering osteoclasts, decreasing alveolar bone resorption, and also increasing BMP2 expression and alveolar bone regeneration.
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