Evidence map›Paper›PMID 28935998›Full record

ArticleIsrael journal of chemistry2017

Theory of amyloid fibril nucleation from folded proteins.

Lingyun Zhang, Jeremy D Schmit

Abstract read
In one paragraph

Article in Israel journal of chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Physical mechanisms of amyloid nucleation on fluid membranes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Article
  8. Assembly Mechanism for Aggregation of Amyloid Fibrils.International journal of molecular sciences · 2018
    Article
  9. Theory of Sequence Effects in Amyloid Aggregation.The journal of physical chemistry. B · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Lingyun ZhangDepartment of Physics, Kansas State University, Manhattan, KS 66506, USA.
Jeremy D SchmitDepartment of Physics, Kansas State University, Manhattan, KS 66506, USA.
Institute of Physics · CNKansas State University · US

Funding

Theoretical and computational modeling of amyloid aggregationR01GM107487 · NIGMS · KANSAS STATE UNIVERSITY · PI SCHMIT, JEREMY DAVID · 2014 to 2018
$1.4M
NIGMS NIH HHS R01 GM107487
6 · The paper itself

Abstract

We present a theoretical model for the nucleation of amyloid fibrils. In our model we use helix-coil theory to describe the equilibrium between a soluble native state and an aggregation-prone unfolded state. We then extend the theory to include oligomers with

Indexed as

aggregationAmyloid beta-peptidesBiophysicsFibrous proteinsProtein models

Identifiers

PMID28935998
PMCPMC5602581
OpenAlexW2581381516

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.