ArticleScientific reports2017
Intergrative metabolomic and transcriptomic analyses unveil nutrient remobilization events in leaf senescence of tobacco.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 90 citations in OpenAlex.
- Leaf development is associated with coupled metabolome-fungi trajectories in the phyllosphere of Panax ginseng.BMC plant biology · 2026Article
- Comprehensive effects of functional agents on growth, nutrient accumulation, and rhizosphere bacterial communities in flue-cured tobacco (Frontiers in plant science · 2026Article
- Diversification of tobacco phytoene-synthase-encoding genes coordinates carotenoid flux, strigolactone biosynthesis, and cold responses.Frontiers in plant science · 2026Article
- Dynamic multi-omics analysis reveals the correlation between aroma compounds and symbiotic microbial community during tobacco leaf aging process.BMC plant biology · 2025Article
- Effects of different intercropping systems on soil properties and tobacco yield and quality.Scientific reports · 2025Article
- Integrated analysis of physiological and metabolic data uncovers essential dynamic mechanisms involved in the maturation of cigar tobacco leaves.Scientific reports · 2024Article
- From Division to Death: Metabolomic Analysis ofPlants (Basel, Switzerland) · 2024Article
- Integrated proteome and metabolome analysis of the penultimate internodes revealing remobilization efficiency in contrasting barley genotypes under water stress.Scientific reports · 2024Article
- Integrative physiological and transcriptome analysis unravels the mechanism of low nitrogen use efficiency in burley tobacco.Plant direct · 2024Article
- Identification of transcription factors associated with leaf senescence in tobacco.Scientific reports · 2024Article
- Effects of Maturation on Antibacterial Properties of Vietnamese Mango (Molecules (Basel, Switzerland) · 2024Article
- Plant Heterotrophic Cultures: No Food, No Growth.Plants (Basel, Switzerland) · 2024Review
- Exploring Influence of Production Area and Harvest Time on Specialized Metabolite Content ofAntioxidants (Basel, Switzerland) · 2024Article
- Proteomic and metabolomic revealed the effect of shading treatment on cigar tobacco.Frontiers in plant science · 2024Article
- Analysis of Nitrogen Dynamics and Transcriptomic Activity Revealed a Pivotal Role of Some Amino Acid Transporters in Nitrogen Remobilization in Poplar Senescing Leaves.Plants (Basel, Switzerland) · 2023Article
- The ABA-AtNAP-SAG113 PP2C module regulates leaf senescence by dephoshorylating SAG114 SnRK3.25 in Arabidopsis.Molecular horticulture · 2023Article
- Differentiation of Mountain- and Garden-Cultivated Ginseng with Different Growth Years Using HS-SPME-GC-MS Coupled with Chemometrics.Molecules (Basel, Switzerland) · 2023Article
- Widely untargeted metabolomic profiling unearths metabolites and pathways involved in leaf senescence and N remobilization in spring-cultivated wheat under different N regimes.Frontiers in plant science · 2023Article
- Profiling the role of microorganisms in quality improvement of the aged flue-cured tobacco.BMC microbiology · 2022Article
- Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence inCells · 2022Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaf senescence in plants is a coordinated process that involves remobilization of nutrients from senescing leaves to sink tissues. The molecular events associated with nutrient remobilization are however not well understood. In this study the tobacco system with a source-sink relationship between different leaf positions was used in analyzing the spatiotemporal changes of 76 metabolites from leaves at 3 different stalk positions and 8 developmental stages. The metabolomic data was then compared with RNA-seq data from the same samples to analyze the activities of the metabolic pathways that are important for nutrient remobilization. Integrative analyses on metabolites accumulation and expression changes of enzyme-encoding genes in corresponding metabolic pathways indicated a significant up-regulation of the tricarboxylic acid cycle and related metabolism of sugars, amino acids and fatty acids, suggesting the importance of energy metabolism during leaf senescence. Other changes of the metabolism during tobacco leaf senescence include increased activities of the GS/GOGAT cycle which is responsible for nitrogen recycling, and increased accumulation of nicotine. The results also suggested that a number of compounds seemed to be transported from senescing leaves at lower positions to sink leaves at upper positions. Some of these metabolites could play a role in nutrient remobilization.
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