SynthesisScientific reports2017
Electrophysiological Studies in Thyroid Associated Orbitopathy: A Systematic Review.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Antithymocyte Globulin as Second-Line Therapy in Graves Orbitopathy-Preliminary Results From a Prospective Single-Center Study.Frontiers in endocrinology · 2022Trial
- Multifocal visual evoked potential in thyroid associated ophthalmopathy.Documenta ophthalmologica. Advances in ophthalmology · 2026Observational
- Investigating the Correlation Between Choroidal Alteration and Visual Function Metrics in Dysthyroid Optic Neuropathy.Translational vision science & technology · 2026Article
- Exploring the Etiologies of Acquired Unilateral Proptosis: A Literature Review with Case Presentations.Archives of plastic surgery · 2026Article
- Restoration of vision by combined experimental antithymocyte therapy, and orbital radiation with high-dose steroids for severe, acute, steroid-refractory, congestive thyroid orbitopathy.Documenta ophthalmologica. Advances in ophthalmology · 2024Article
- Visual function changes of dysthyroid optic neuropathy and ROC curve analysis for early diagnostic indicators.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Optical coherence tomography and electrophysiological analysis of proptotic eyes due to thyroid-associated ophthalmopathy.International ophthalmology · 2023Article
- Functional and Morphological Changes in the Visual Pathway in Patients with Graves' Orbitopathy.Journal of clinical medicine · 2022Article
- RAPD as a clinical alert for early evidence of dysthyroid optic neuropathy.Journal of family medicine and primary care · 2022Article
- Clinical electrophysiology of the optic nerve and retinal ganglion cells.Eye (London, England) · 2021Review
- Retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after orbital decompression for dysthyroid optic neuropathy.International ophthalmology · 2021Article
- Dysthyroid optic neuropathy: evaluation and management.Journal of endocrinological investigation · 2021Review
- Early macular and peripapillary vasculature dropout in active thyroid eye disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Observational
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysthyroid optic neuropathy (DON) is the commonest cause of blindness in thyroid associated orbitopathy (TAO). While diagnosis remains clinical, objective tests for eyes with early or equivocal findings are lacking. Various electrophysiological studies (EPS) have been reported, yet the types and parameters useful for DON remain inconclusive. We performed a systematic literature search in MEDLINE, EMBASE and the Cochrane databases via the OVID platform up to August 20, 2017. 437 records were identified for screening and 16 original studies (1327 eyes, 787 patients) were eligible for review. Pattern visual evoked potential (pVEP) was the most frequently studied EPS. Eyes of TAO patients with DON showed delayed P100 latencies, decreased P100 amplitudes or delayed N75 latencies during pVEP, compared to those without or healthy controls. Due to study heterogeneity, no quantitative analysis was possible. This review highlights the most common type (pVEP) and useful parameters (P100 latency and amplitude) of EPS, and supports further research on them using standardized testing conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.