ArticleScientific reports2017
Exploring genetic influences underlying acute aerobic exercise effects on motor learning.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The effect of dopamine D2-like receptor blockade on human motor performance and skill acquisition.Scientific reports · 2026Trial
- Dopamine D2 Receptor Modulates Exercise Related Effect on Cortical Excitation/Inhibition and Motor Skill Acquisition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Trial
- High-intensity cardiovascular exercise facilitates online motor skill learning, with no effect of BDNF genotype.NPJ science of learning · 2026Article
- Motor cortical excitability and inhibition are differentially modulated by aerobic exercise intensity.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Brain-derived neurotrophic factor gene polymorphism rs6265 and elite athlete status in four independent populations.Biology of sport · 2025Article
- Gating of Neuroplasticity: Effects and Mechanisms of Acute Aerobic Exercise as a Brain Stimulation for the Sensorimotor Cortex.Advances in neurobiology · 2025Review
- Article
- Review
- Current Methodological Pitfalls and Caveats in the Assessment of Exercise-Induced Changes in Peripheral Brain-Derived Neurotrophic Factor: How Result Reproducibility Can Be Improved.Frontiers in neuroergonomics · 2021Review
- HIIT the Road Jack: An Exploratory Study on the Effects of an Acute Bout of Cardiovascular High-Intensity Interval Training on Piano Learning.Frontiers in psychology · 2020Article
- Acute high-intensity and moderate-intensity interval exercise do not change corticospinal excitability in low fit, young adults.PloS one · 2020Article
- Effects of Exercise on Cognitive Performance in Children and Adolescents with ADHD: Potential Mechanisms and Evidence-based Recommendations.Journal of clinical medicine · 2019Review
- The Beneficial Effect of Acute Exercise on Motor Memory Consolidation is Modulated by Dopaminergic Gene Profile.Journal of clinical medicine · 2019Article
- The effect of energy-matched exercise intensity on brain-derived neurotrophic factor and motor learning.Neurobiology of learning and memory · 2018Article
- Acute cardiovascular exercise does not enhance locomotor learning in people with stroke.The Journal of physiology · 2018Article
- A Single Bout of Aerobic Exercise Improves Motor Skill Consolidation in Parkinson's Disease.Frontiers in aging neuroscience · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of the current work was to evaluate whether the effects of acute aerobic exercise on motor learning were dependent on genetic variants impacting brain-derived neurotrophic factor (BDNF val66met polymorphism) and the dopamine D2 receptor (DRD2/ANKK1 glu713lys polymorphism) in humans. A retrospective analysis was performed to determine whether these polymorphisms influence data from our two previous studies, which both demonstrated that a single bout of aerobic exercise prior to motor practice enhanced implicit motor learning. Here, our main finding was that the effect of acute aerobic exercise on motor learning was dependent on DRD2/ANKK1 genotype. Motor learning was enhanced when aerobic exercise was performed prior to skill practice in glu/glu homozygotes, but not lys allele carriers. In contrast, the BDNF val66met polymorphism did not impact the exercise effect. The results suggest that the dopamine D2 receptor may be involved in acute aerobic exercise effects on motor learning. Such genetic information could inform the development of individualized aerobic exercise strategies to promote motor learning.
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