ArticleScientific reports2017
Whole genome sequencing, molecular typing and in vivo virulence of OXA-48-producing Escherichia coli isolates including ST131 H30-Rx, H22 and H41 subclones.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Antimicrobial resistance in food-associatedBioscience of microbiota, food and health · 2024Review
- Production of OXA-48 carbapenemase acts as an independent risk factor for poor outcome in Klebsiella pneumoniae infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- A Study in a Regional Hospital of a Mid-Sized Spanish City Indicates a Major Increase in Infection/Colonization by Carbapenem-Resistant Bacteria, Coinciding with the COVID-19 Pandemic.Antibiotics (Basel, Switzerland) · 2021Article
- Whole Genome Analysis of EnvironmentalGenes · 2021Article
- Molecularly defined extraintestinal pathogenicVirulence · 2020Article
- Molecular Characteristics of Extraintestinal PathogenicMicroorganisms · 2020Article
- Genomic Characterization ofAntibiotics (Basel, Switzerland) · 2020Article
- Clonal Structure, Virulence Factor-encoding Genes and Antibiotic Resistance ofAntibiotics (Basel, Switzerland) · 2020Article
- Whole Genome Sequencing and Characteristics ofFrontiers in microbiology · 2020Article
- High Prevalence of ST131 Subclades C2-Frontiers in cellular and infection microbiology · 2020Article
- Sequence Types, Clonotypes, Serotypes, and Virotypes of Extended-Spectrum β-Lactamase-ProducingFrontiers in microbiology · 2019Article
- Pathogenicity of Clinical OXA-48 Isolates and Impact of the OXA-48 IncL Plasmid on Virulence and Bacterial Fitness.Frontiers in microbiology · 2019Article
- Resistance to Carbapenems in Non-Typhoidal Salmonella enterica Serovars from Humans, Animals and Food.Veterinary sciences · 2018Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbapenem-resistant Enterobacteriaceae, including the increasingly reported OXA-48 Escherichia coli producers, are an emerging public health threat worldwide. Due to their alarming detection in our healthcare setting and their possible presence in the community, seven OXA-48-producing, extraintestinal pathogenic E. coli were analysed by whole genome sequencing as well as conventional tools, and tested for in vivo virulence. As a result, five E. coli OXA-48-producing subclones were detected (O25:H4-ST131/PST43-fimH30-virotype E; O25:H4-ST131/PST9-fimH22-virotype D5, O16:H5-ST131/PST506-fimH41; O25:H5-ST83/PST207 and O9:H25-ST58/PST24). Four ST131 and one ST83 isolates satisfied the ExPEC status, and all except the O16:H5 ST131 isolate were UPEC. All isolates exhibited local inflammatory response with extensive subcutaneous necrosis but low lethality when tested in a mouse sepsis model. The bla
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