Evidence map›Paper›PMID 28935867›Full record

ArticleScientific reports2017

S100A4 contributes to colitis development by increasing the adherence of Citrobacter rodentium in intestinal epithelial cells.

Jinhua Zhang, Ying Jiao, Shasha Hou, Tian Tian, Qi Yuan, Huaijie Hao, Zhenlong Wu, Xuexiang Bao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity.Cancer immunology, immunotherapy : CII · 2024
    Article
  4. Smad4 Deficiency in S100A4International journal of biological sciences · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. S100 proteins as therapeutic targets.Biophysical reviews · 2018
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jinhua ZhangCollege of Life Science and Bioengineering, Beijing Jiaotong University, Beijing, 100044, P.R. China. zhangjh@bjtu.edu.cn.ORCID 0000-0001-8957-8893
Ying JiaoSchool of Life Sciences, Northeast Normal University, Changchun, 130024, P.R. China.
Shasha HouCollege of Life Science and Bioengineering, Beijing Jiaotong University, Beijing, 100044, P.R. China.
Tian TianCollege of Life Science and Bioengineering, Beijing Jiaotong University, Beijing, 100044, P.R. China.
Qi YuanCollege of Life Science and Bioengineering, Beijing Jiaotong University, Beijing, 100044, P.R. China.
Huaijie HaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, P.R. China.
Zhenlong WuState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, P. R. China.
Xuexiang BaoSchool of Life Sciences, Northeast Normal University, Changchun, 130024, P.R. China. xuexiangb@aliyun.com.
Beijing Jiaotong University · CNNortheast Normal University · CNChina Agricultural University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

S100A4 has been implicated in cancer and several inflammatory diseases, but its role in inflammatory bowel disease has not been well investigated. Here, upon infection with Citrobacter rodentium, a model for enteropathogenic Escherichia coli infection in humans, induced the infiltration of a large number of S100A4

Indexed as

AnimalsBacterial AdhesionCell Line, TumorCitrobacter rodentiumColitisCytokinesEnterobacteriaceae InfectionsEpithelial CellsHost-Pathogen InteractionsHumansIntestinal MucosaMacrophagesMice, Inbred C57BLMice, KnockoutPhagocytosisS100 Calcium-Binding Protein A4CytokinesS100 Calcium-Binding Protein A4

Identifiers

PMID28935867
PMCPMC5608709
OpenAlexW2754854804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.