Trial reportEnvironmental health perspectives2017
Randomized Trial of Interventions to Improve Childhood Asthma in Homes with Wood-burning Stoves.
Trial report in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00807183 (Indoor Woodsmoke PM and Asthma), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Indoor Woodsmoke PM and Asthma: a Randomized Trial
Who cites it
26 citing papers in PubMed, 54 citations in OpenAlex.
- Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Trial
- Efficacy of Air Filtration and Education Interventions on Indoor Fine Particulate Matter and Child Lower Respiratory Tract Infections among Rural U.S. Homes Heated with Wood Stoves: Results from the KidsAIR Randomized Trial.Environmental health perspectives · 2022Trial
- Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.Environmental health : a global access science source · 2022Trial
- A review of indoor air quality interventions and child neurobehavioral outcomes.Pediatric research · 2026Review
- Uterine Vulnerability to Environmental PMInternational journal of molecular sciences · 2026Article
- Article
- [Mitigating the Health Effects of Particulate Matter: A Narrative Review of Intervention Studies].Jugan geon-gang gwa jilbyeong · 2025Review
- The Airport, Air Quality and Asthma (AAA) Indoor Air Intervention Trial for Children with Asthma: Protocol for a Community Based Study in South King County, Washington State.Research square · 2025Article
- Nonparametric analysis of quality-of-life measures for randomized clustered design: the R package npclust.BMC medical research methodology · 2025Article
- Randomized trial in rural Native American homes heated with wood stoves: results from the EldersAIR study.Air quality, atmosphere, & health · 2024Article
- Recent Insights into the Environmental Determinants of Childhood Asthma.Current allergy and asthma reports · 2024Review
- Testing of a novel questionnaire of Household Exposure to Wood Smoke.PLOS global public health · 2023Article
- Housing conditions and respiratory morbidity in Indigenous children in remote communities in Northwestern Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Children's Particulate Matter Exposure Characterization as Part of the New Hampshire Birth Cohort Study.International journal of environmental research and public health · 2021Article
- The Effect of Particulate Matter Reduction by Indoor Air Filter Use on Respiratory Symptoms and Lung Function: A Systematic Review and Meta-analysis.Allergy, asthma & immunology research · 2021Article
- Intervention of Particulate Matter: What Can We Do for Asthmatic Patients?Allergy, asthma & immunology research · 2021Article
- Creating Clean Air Spaces During Wildland Fire Smoke Episodes: Web Summit Summary.Frontiers in public health · 2021Article
- The home air in agriculture pediatric intervention (HAPI) trial: Rationale and methods.Contemporary clinical trials · 2020Article
- Impact of Air Pollution on Asthma Outcomes.International journal of environmental research and public health · 2020Review
- Personal strategies to minimise effects of air pollution on respiratory health: advice for providers, patients and the public.The European respiratory journal · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHousehold air pollution due to biomass combustion for residential heating adversely affects vulnerable populations. Randomized controlled trials to improve indoor air quality in homes of children with asthma are limited, and no such studies have been conducted in homes using wood for heating.
objectivesOur aims were to test the hypothesis that household-level interventions, specifically improved-technology wood-burning appliances or air-filtration devices, would improve health measures, in particular Pediatric Asthma Quality of Life Questionnaire (PAQLQ) scores, relative to placebo, among children living with asthma in homes with wood-burning stoves.
methodsA three-arm placebo-controlled randomized trial was conducted in homes with wood-burning stoves among children with asthma. Multiple preintervention and postintervention data included PAQLQ (primary outcome), peak expiratory flow (PEF) monitoring, diurnal peak flow variability (dPFV, an indicator of airway hyperreactivity) and indoor particulate matter (PM) PM2.5.
resultsRelative to placebo, neither the air filter nor the woodstove intervention showed improvement in quality-of-life measures. Among the secondary outcomes, dPFV showed a 4.1 percentage point decrease in variability [95% confidence interval (CI)=-7.8 to -0.4] for air-filtration use in comparison with placebo. The air-filter intervention showed a 67% (95% CI: 50% to 77%) reduction in indoor PM2.5, but no change was observed with the improved-technology woodstove intervention.
conclusionsAmong children with asthma and chronic exposure to woodsmoke, an air-filter intervention that improved indoor air quality did not affect quality-of-life measures. Intent-to-treat analysis did show an improvement in the secondary measure of dPFV.
trial registrationClincialTrials.gov NCT00807183. https://doi.org/10.1289/EHP849.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.