ReviewBMC medicine2017
Lifestyle precision medicine: the next generation in type 2 diabetes prevention?
Review in BMC medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- Does the Impact of Intensive Lifestyle Intervention on Cardiovascular Disease Risk Vary According to Frailty as Measured via Deficit Accumulation?The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Trial
- Response heterogeneity to lifestyle intervention among Latino adolescents.Pediatric diabetes · 2020Trial
- DNA methylation changes and improved sleep quality in adults with obstructive sleep apnea and diabetes.BMJ open diabetes research & care · 2019Trial
- Type 2 diabetes prevention across the life course.Nature medicine · 2026Review
- What Is Precision Psychotherapy?The Journal of medicine and philosophy · 2026Article
- Dried blood spots capture a wide range of metabolic pathways and biological changes associated with exercise.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Trajectories of healthy lifestyle index and prediabetes risk of adult workers in Japan.Communications medicine · 2025Article
- Genetic effects on gestational diabetes mellitus and their interactions with environmental factors among Japanese women.Journal of human genetics · 2025Article
- LSD600: the first corpus of biomedical abstracts annotated with lifestyle-disease relations.Database : the journal of biological databases and curation · 2025Article
- From molecular mechanisms of prostate cancer to translational applications: based on multi-omics fusion analysis and intelligent medicine.Health information science and systems · 2024Review
- PowerAI-Diabetes: Review of glycemic and lipid variability to predict cardiovascular events in Chinese diabetic population.npj metabolic health and disease · 2024Review
- Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review.Communications medicine · 2023Article
- Health educationFrontiers in public health · 2022Article
- Towards precision cardiometabolic prevention: results from a machine learning, semi-supervised clustering approach in the nationwide population-based ORISCAV-LUX 2 study.Scientific reports · 2021Article
- Precision Health Care Elements, Definitions, and Strategies for Patients with Diabetes: A Literature Review.International journal of environmental research and public health · 2021Review
- Next-generation epidemiology: the role of high-resolution molecular phenotyping in diabetes research.Diabetologia · 2020Review
- Analysis of Diabetes Mellitus-Related Amputations in the State of Espírito Santo, Brazil.Medicina (Kaunas, Lithuania) · 2020Article
- Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology.American journal of physiology. Heart and circulatory physiology · 2020Review
- Metabolically Healthy Obesity-Heterogeneity in Definitions and Unconventional Factors.Metabolites · 2020Review
- Management and Prevention Strategies for Non-communicable Diseases (NCDs) and Their Risk Factors.Frontiers in public health · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The driving force behind the current global type 2 diabetes epidemic is insulin resistance in overweight and obese individuals. Dietary factors, physical inactivity, and sedentary behaviors are the major modifiable risk factors for obesity. Nevertheless, many overweight/obese people do not develop diabetes and lifestyle interventions focused on weight loss and diabetes prevention are often ineffective. Traditionally, chronically elevated blood glucose concentrations have been the hallmark of diabetes; however, many individuals will either remain 'prediabetic' or regress to normoglycemia. Thus, there is a growing need for innovative strategies to tackle diabetes at scale. The emergence of biomarker technologies has allowed more targeted therapeutic strategies for diabetes prevention (precision medicine), though largely confined to pharmacotherapy. Unlike most drugs, lifestyle interventions often have systemic health-enhancing effects. Thus, the pursuance of lifestyle precision medicine in diabetes seems rational. Herein, we review the literature on lifestyle interventions and diabetes prevention, describing the biological systems that can be characterized at scale in human populations, linking them to lifestyle in diabetes, and consider some of the challenges impeding the clinical translation of lifestyle precision medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.