Evidence map›Paper›PMID 28934351›Full record

ReviewPLoS pathogens2017

The microbiome and the hallmarks of cancer.

Laura E Fulbright, Melissa Ellermann, Janelle C Arthur

Registry-linked trialAbstract readReview
In one paragraph

Review in PLoS pathogens, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04735289 (Evaluation of Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma), which is not on this map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04735289 unknown statusnot on this mapstarted 2021, after this paper: background citation

Evaluation of Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma

Typeobservational_patient_registrySponsorIstituto Ortopedico RizzoliRan2021 to 2024Enrolled810ConditionsOsteosarcoma, Ewing SarcomaArmsEPIC-COS Food Frequency Questionnaire diet Evaluation, Metabolome, Microbiota, Lymphocytes subpopulations
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Fujita medical journal · 2026
    Article
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  12. The Vaginal Microbiome: Setting the Stage for Cancer?The Journal of infectious diseases · 2025
    Article
  13. Article
  14. Charting cancer's course: revealing the role of diet, exercise, and the microbiome in cancer evolution and immunotherapy response.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  15. Review
  16. Article
  17. Review
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  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura E FulbrightDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID 0000-0003-3212-3390
Melissa EllermannDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-8942-6889
Janelle C ArthurDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID 0000-0002-4796-0207

Funding

Intestinal inflammation and genotoxicity of the colonic-adherent microbiotaK01DK103952 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ARTHUR, JANELLE C · 2014 to 2018
$758k
NIDDK NIH HHS K01 DK103952NIH HHS 1K01DK103952-01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MicrobiotaAnimalsHumansNeoplasms

Identifiers

PMID28934351
PMCPMC5608396

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.