ArticlePloS one2017
Logical inconsistencies in time trade-off valuation of EQ-5D-5L health states: Whose fault is it?
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Estimation of an EORTC QLU-C10 Value Set for Spain Using a Discrete Choice Experiment.PharmacoEconomics · 2021Trial
- Who Prefers Death to Life in Composite Time Trade-off Interviews, and Why? A Mixed-Methods Study among Asians in Singapore.The patient · 2026Article
- Health-related quality of life in poverty-alleviated individuals living with chronic conditions: a cross-sectional survey from an impoverished county in China.Scientific reports · 2026Article
- Valuation of cognition bolt-ons for EQ-5D-5L in Japan: A comparative analysis of scaling factor and conventional models.Journal of Alzheimer's disease : JAD · 2025Article
- VAS value set still has its own application value compare with TTO value set of EQ-5D-3L in Chinese population.BMC medical research methodology · 2025Article
- Article
- Health State Utilities Associated With Treatment Burden in Cystic Fibrosis: A Patient Valuation Study.CHEST pulmonary · 2025Article
- Chinese utility weights for the EORTC cancer-specific utility instrument QLU-C10D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Exploring non-iterative time trade-off methods for valuation of EQ-5D-5L health states.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- The Egyptian EQ-5D-5L Extensive Pilot Study: Lessons Learned.PharmacoEconomics · 2023Article
- Disutilities Associated with Intravenous Iron Infusions: Results from a Time Trade-off Survey and Diminishing Marginal Utility Model for Treatment Attributes in China.Patient related outcome measures · 2023Article
- Estimating the EQ-5D-5L value set for the Philippines.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Measuring the acceptability of EQ-5D-3L health states for different ages: a new adaptive survey methodology.The European journal of health economics : HEPAC : health economics in prevention and care · 2022Article
- Do health preferences differ among Asian populations? A comparison of EQ-5D-5L discrete choice experiments data from 11 Asian studies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Rural population's preferences matter: a value set for the EQ-5D-3L health states for China's rural population.Health and quality of life outcomes · 2022Article
- Eliciting health state utilities for Aromatic L-amino Acid Decarboxylase (AADC) deficiency: a UK vignette study.Journal of patient-reported outcomes · 2021Article
- Valuation of SF-6Dv2 Health States in China Using Time Trade-off and Discrete-Choice Experiment with a Duration Dimension.PharmacoEconomics · 2021Article
- Eliciting Health State Utilities for Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency: A Vignette Study in France.Patient related outcome measures · 2021Article
- EORTC QLU-C10D value sets for Austria, Italy, and Poland.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInconsistency in the time trade-off (TTO) task in EQ-5D-5L occurs when a respondent gives a higher value to a logically worse health state, the occurrence of inconsistency compromises the quality of the data. It is not yet clear which factors are associated with individual level inconsistency. Relating inconsistency to the characteristics of the respondent, interviewer, and the interview process could be helpful in understanding the causes of inconsistency. The objective of this paper is to discover the factors associated with individual level inconsistencies.
methodsTwenty interviewers interviewed 1,296 respondents and each respondent valued 10 health states using the EQ-VT platform in 5 cities in China. At the respondent level, inconsistency was identified in terms of severity and quantity and related to the respondent's background characteristics, the time and iterations spent on the wheelchair example task, and the formal TTO tasks, using multilevel multinomial regression analyses. Interviewers' impact on inconsistencies was analyzed using single level multinomial regression analyses.
resultsIn the full dataset, slight inconsistency was more related to the interview process (Time spent on TTO task: RRR = 1.246 with 95%CI: 1.076,1.441; time spent on Wheelchair example: RRR = 0.815 with 95%CI:0.699,0.952) while severe inconsistency was more related to respondent's gender (Gender: RRR = 2.347 with 95%CI:1.429,3.855). One Interviewer (Interviewer 7: RRR = 7.335 with 95%CI:1.908,28.195) and interviewer's experience (Sequence: RRR = 0.511 with 95%CI:0.385,0.678) in general showed strong influence over inconsistency in the TTO task.
conclusionIn conclusion, logical inconsistency in the valuation of EQ-5D-5L health states is associated not only with respondents' characteristics but also with interviewers' performance and the interview process. The role of interviewers and the importance of interviewer training may be more crucial than hitherto believed. This finding could be generalizable to other interviewer-administered health-state valuation study.
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