Evidence map›Paper›PMID 28934169›Full record

ReviewMolecules (Basel, Switzerland)2017

Function Oriented Molecular Design: Dendrimers as Novel Antimicrobials.

Sandra García-Gallego, Gianluigi Franci, Annarita Falanga, Rafael Gómez, Veronica Folliero, Stefania Galdiero, Francisco Javier de la Mata, Massimiliano Galdiero

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  8. Smart nanoparticles for cancer therapy.Signal transduction and targeted therapy · 2023
    Review
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  17. Silver (I)Pharmaceutics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sandra García-GallegoOrganic and Inorganic Chemistry Department, Universidad de Alcalá, Campus Universitario, E-28871 Alcalá de Henares, Spain. sagg@kth.se.
Gianluigi FranciDepartment of Experimental Medicine, II University of Naples, Via Costantinopoli 16, 80138 Naples, Italy. gianluigi.franci@unicampania.it.
Annarita FalangaDepartment of Pharmacy, University of Naples "Federico II", Via Mezzocannone 16, 80134 Napoli, Italy. annarita.falanga@unina.it.
Rafael GómezOrganic and Inorganic Chemistry Department, Universidad de Alcalá, Campus Universitario, E-28871 Alcalá de Henares, Spain. rafael.gomez@uah.es.
Veronica FollieroDepartment of Experimental Medicine, II University of Naples, Via Costantinopoli 16, 80138 Naples, Italy. veronica.folliero@unicampania.it.
Stefania GaldieroInteruniversity Research Centre on Bioactive Peptides (CiRPEB), University of Naples "Federico II", Via Mezzocannone 16, 80134 Naples, Italy. stefania.galdiero@unina.it.
Francisco Javier de la MataOrganic and Inorganic Chemistry Department, Universidad de Alcalá, Campus Universitario, E-28871 Alcalá de Henares, Spain. javier.delamata@uah.es.
Massimiliano GaldieroDepartment of Experimental Medicine, II University of Naples, Via Costantinopoli 16, 80138 Naples, Italy. massimiliano.galdiero@unina2.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntiviral AgentsDendrimersNanostructuresAnti-Bacterial AgentsAnti-Infective AgentsAntiviral AgentsDendrimersantibacterialantimicrobialantiparasiticantiviraldeliverydendrimerspreparationstructure

Identifiers

PMID28934169
PMCPMC6151464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.