Evidence map›Paper›PMID 28934165›Full record

ArticleInternational journal of molecular sciences2017

Salmonella O48 Serum Resistance is Connected with the Elongation of the Lipopolysaccharide O-Antigen Containing Sialic Acid.

Aleksandra Pawlak, Jacek Rybka, Bartłomiej Dudek, Eva Krzyżewska, Wojciech Rybka, Anna Kędziora, Elżbieta Klausa, Gabriela Bugla-Płoskońska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aleksandra PawlakDepartment of Microbiology, Institute of Genetics and Microbiology, University of Wrocław, 51-148 Wrocław, Poland. aleksandra.pawlak@uwr.edu.pl.
Jacek RybkaDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wrocław, Poland. rybka@iitd.pan.wroc.pl.
Bartłomiej DudekDepartment of Microbiology, Institute of Genetics and Microbiology, University of Wrocław, 51-148 Wrocław, Poland. bartlomiej.dudek@uwr.edu.pl.
Eva KrzyżewskaDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wrocław, Poland. eva.krzyzewska@iitd.pan.wroc.pl.ORCID 0000-0002-5581-1690
Wojciech RybkaDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wrocław, Poland. wrybka@iitd.pan.wroc.pl.
Anna KędzioraDepartment of Microbiology, Institute of Genetics and Microbiology, University of Wrocław, 51-148 Wrocław, Poland. anna.kedziora@uwr.edu.pl.ORCID 0000-0002-0947-1402
Elżbieta KlausaRegional Centre of Transfusion Medicine and Blood Bank, 50-345 Wrocław, Poland. e.klausa@rckik.wroclaw.pl.
Gabriela Bugla-PłoskońskaDepartment of Microbiology, Institute of Genetics and Microbiology, University of Wrocław, 51-148 Wrocław, Poland. gabriela.bugla-ploskonska@uwr.edu.pl.
University of Wrocław · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PLNational Bank of Poland · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complement is one of the most important parts of the innate immune system. Some bacteria can gain resistance against the bactericidal action of complement by decorating their outer cell surface with lipopolysaccharides (LPSs) containing a very long O-antigen or with specific outer membrane proteins. Additionally, the presence of sialic acid in the LPS molecules can provide a level of protection for bacteria, likening them to human cells, a phenomenon known as molecular mimicry.

Indexed as

Complement ActivationComplement C3Culture MediaDrug Resistance, BacterialGas Chromatography-Mass SpectrometryHost-Pathogen InteractionsHumansMicrobial ViabilityMolecular MimicryN-Acetylneuraminic AcidO AntigensSalmonellaSerumComplement C3Culture MediaN-Acetylneuraminic AcidO Antigenscomplementlipopolysaccharidereptile-associated salmonellosisSalmonellaserum resistancesialic acid

Identifiers

PMID28934165
PMCPMC5666704
OpenAlexW2758835600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.