ArticleGenetics in medicine : official journal of the American College of Medical Genetics2018
Trends in utilization and costs of BRCA testing among women aged 18-64 years in the United States, 2003-2014.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- All HER2-negative breast cancer patients need gBRCA testing: cost-effectiveness and clinical benefits.British journal of cancer · 2023Trial
- Polygenic backgrounds influence phenotypic consequences of variants in cells, individuals, and populations.Cell genomics · 2026Review
- Use of Family Relationships in Commercial Claims Data to Characterize Clinical Events of Patients withAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Prostate-specific antigen screening at low thresholds of men with pathogenic BRCA1/2 variants.Prostate cancer and prostatic diseases · 2025Article
- BRCA genetic testing utilization and expenditures among privately insured adults in the United States, 2013 to 2022.Genetics in medicine : official journal of the American College of Medical Genetics · 2025Article
- Genetic Testing Among Breast Cancer Patients in the Eastern Region of Saudi Arabia: Single-Center Experience.Journal of epidemiology and global health · 2024Article
- Survivorship after adolescent and young adult cancer: models of care, disparities, and opportunities.Journal of the National Cancer Institute · 2024Article
- Hereditary Cancer Clinics Improve Adherence to NCCN Germline Testing Guidelines for Pancreatic Cancer.Journal of the National Comprehensive Cancer Network : JNCCN · 2024Article
- Promoters of BRCA testing under insurance coverage for non-metastatic breast cancer patients in Japan: a retrospective cohort study.Breast cancer (Tokyo, Japan) · 2023Article
- Attitudes towards and sociodemographic determinants of genetic test usage in the USA; data from the Health Information National Trend Survey, 2020.Journal of genetic counseling · 2023Article
- Adolescent and young adult cancers: unmet needs and closing the gaps.Current opinion in pediatrics · 2023Review
- Challenges and Opportunities in Engaging Primary Care Providers in BRCA Testing: Results from the BFOR Study.Journal of general internal medicine · 2022Observational
- Analyzing Precision Medicine Utilization with Real-World Data: A Scoping Review.Journal of personalized medicine · 2022Article
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- Cancer genetic testing in marginalized groups during an era of evolving healthcare reform.Journal of cancer policy · 2021Review
- Impact of a Genetic Evaluation Initiative to Increase Access to Genetic Services for Adolescent and Young Adults at a Tertiary Cancer Hospital.Journal of adolescent and young adult oncology · 2021Article
- Racial and Ethnic Differences in BRCA1/2 and Multigene Panel Testing Among Young Breast Cancer Patients.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021Article
- Surgeon and medical oncologist peer network effects on the uptake of the 21-gene breast cancer recurrence score assay.Cancer medicine · 2021Article
- Integrating fundamental cause theory and Bourdieu to explain pathways between socioeconomic status and health: the case of health insurance denials for genetic testing.Sociology of health & illness · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
PurposeWe examined 12-year trends in BRCA testing rates and costs in the context of clinical guidelines, national policies, and other factors.MethodsWe estimated trends in BRCA testing rates and costs from 2003 to 2014 for women aged 18-64 years using private claims data and publicly reported revenues from the primary BRCA testing provider.ResultsThe percentage of women with zero out-of-pocket payments for BRCA testing increased during 2013-2014, after 7 years of general decline, coinciding with a clarification of Affordable Care Act coverage of BRCA genetic testing. Beginning in 2007, family history accounted for an increasing proportion of women with BRCA tests compared with personal history, coinciding with BRCA testing guidelines for primary care settings and direct-to-consumer advertising campaigns. During 2013-2014, BRCA testing rates based on claims grew at a faster rate than revenues, following 3 years of similar growth, consistent with increased marketplace competition. In 2013, BRCA testing rates based on claims increased 57%, compared with 11% average annual increases over the preceding 3 years, coinciding with celebrity publicity.ConclusionThe observed trends in BRCA testing rates and costs are consistent with possible effects of several factors, including the Affordable Care Act, clinical guidelines and celebrity publicity.
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