Evidence map›Paper›PMID 28933769›Full record

ArticleMolecules (Basel, Switzerland)2017

A Lanosteryl Triterpene from Protorhus longifolia Improves Glucose Tolerance and Pancreatic Beta Cell Ultrastructure in Type 2 Diabetic Rats.

Sihle E Mabhida, Rebamang A Mosa, Dambudzo Penduka, Foluso O Osunsanmi, Phiwayinkosi V Dludla, Tryana G Djarova, Andy R Opoku

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Chrysin protects cardiac H9c2 cells against HMolecular and cellular biochemistry · 2023
    Article
  3. Herbal Medicines Targeting the ImprovedEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sihle E MabhidaDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. sihlemabhida@gmail.com.
Rebamang A MosaDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. rebamang@gmail.com.
Dambudzo PendukaDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. propafadzo@gmail.com.
Foluso O OsunsanmiDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. alafin21@yahoo.com.
Phiwayinkosi V DludlaBiomedical Research and innovation Platform (BRIP), South African Medical Research Council, Tygerberg 7505, South Africa. pdludla@mrc.ac.za.ORCID 0000-0001-5965-3610
Tryana G DjarovaDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. drdjarova@yahoo.com.
Andy R OpokuDepartment of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, South Africa. opokuA@unizulu.ac.za.
University of Zululand · ZASouth African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes remains one of the leading causes of death worldwide. Persistent hyperglycemia within a diabetic state is implicated in the generation of oxidative stress and aggravated inflammation that is responsible for accelerated modification of pancreatic beta cell structure. Here we investigated whether a lanosteryl triterpene, methyl-3β-hydroxylanosta-9,24-dien-21-oate (RA-3), isolated from

Indexed as

AnacardiaceaeAnimalsAntioxidantsBlood GlucoseDiabetes Mellitus, Type 2Diet, High-FatGlucoseGlucose Tolerance TestHyperglycemiaHypoglycemic AgentsInflammationInsulinInsulin-Secreting CellsInterleukin-6LanosterolOxidative StressAntioxidantsBlood GlucoseCML-1 plant extractGlucoseHypoglycemic AgentsInsulinInterleukin-6Lanosterolmethyl 3-hydroxylanosta-9,24-dien-21-oatePlant ExtractsStreptozocinTriterpenesantioxidantshyperglycemiahyperlipidemiainflammationoxidative stresspancreatic beta cellsProtorhus longifoliatriterpenestype 2 diabetes

Identifiers

PMID28933769
PMCPMC6152316
OpenAlexW2737014550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.