Evidence map›Paper›PMID 28933645›Full record

ArticleOrganogenesis2017

RARα and RARγ reciprocally control K5

Kara A DeSantis, Adam R Stabell, Danielle C Spitzer, Kevin J O'Keefe, Deirdre A Nelson, Melinda Larsen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organogenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. VDR in salivary gland homeostasis and cancer.The Journal of steroid biochemistry and molecular biology · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kara A DeSantisa Graduate program in Molecular, Cellular, Developmental, and Neural Biology , University at Albany, SUNY , Albany , NY , USA.
Adam R Stabellb Department of Biological Science , University at Albany, SUNY , Albany , NY , USA.
Danielle C Spitzera Graduate program in Molecular, Cellular, Developmental, and Neural Biology , University at Albany, SUNY , Albany , NY , USA.
Kevin J O'Keefea Graduate program in Molecular, Cellular, Developmental, and Neural Biology , University at Albany, SUNY , Albany , NY , USA.
Deirdre A Nelsonb Department of Biological Science , University at Albany, SUNY , Albany , NY , USA.
Melinda Larsena Graduate program in Molecular, Cellular, Developmental, and Neural Biology , University at Albany, SUNY , Albany , NY , USA.ORCID 0000-0002-5026-2012
University at Albany, State University of New York · USUniversity of North Carolina at Chapel Hill · US

Funding

Engineering Functional Salivary Glands Using Micropatterned ScaffoldsR01DE022467 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CASTRACANE, JAMES, LARSEN, MELINDA · 2012 to 2016
$2.4M
Engineering Functioning Salivary Glands Using Micropatterned ScaffoldsR56DE022467 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CASTRACANE, JAMES, LARSEN, MELINDA · 2017 to 2017
$653k
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015464 · NCRR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI WICK-PELLETIER, JOAN · 2000 to 2000
$620k
NCRR NIH HHS C06 RR015464NIDCR NIH HHS R01 DE022467NIDCR NIH HHS R56 DE022467
6 · The paper itself

Abstract

Understanding the mechanisms of controlled expansion and differentiation of basal progenitor cell populations during organogenesis is essential for developing targeted regenerative therapies. Since the cytokeratin 5-positive (K5 SUMMARY STATEMENT: RARα and RARγ reciprocally control K5

Indexed as

Gene Expression Regulation, DevelopmentalAC133 AntigenAnimalsCell CycleCell DifferentiationCell LineageCell ProliferationEpithelial CellsKeratinsMiceReceptors, Retinoic AcidRegenerative MedicineRetinoic Acid Receptor alphaRetinoic Acid Receptor gammaSalivary GlandsStem CellsAC133 AntigenKeratinsProm1 protein, mouseRara protein, mouseReceptors, Retinoic AcidRetinoic Acid Receptor alphaRetinoic Acid Receptor gammaAbranching morphogenesisatRcytokeratin 5RARαRARγsalivary gland

Identifiers

PMID28933645
PMCPMC5669212
OpenAlexW2758596610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.