Evidence map›Paper›PMID 28933410›Full record

ReviewDiseases (Basel, Switzerland)2016

Honey and Cancer: Current Status and Future Directions.

Laura M Porcza, Claire Simms, Mridula Chopra

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Understanding the Anticancer Properties of Honey.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Effects ofActa medica Philippina · 2024
    Article
  7. Article
  8. Article
  9. Uses of Natural Honey in Cancer: An Updated Review.Advanced pharmaceutical bulletin · 2022
    Review
  10. Review
  11. Honey and its nutritional and anti-inflammatory value.BMC complementary medicine and therapies · 2021
    Review
  12. Ethnopharmacological study of herbal remedies used for the management of thyroid disorders in Algeria.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Article
  13. Ethnopharmacological study of natural products used for traditional cancer therapy in Algeria.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura M PorczaInstitute of Biomedical and Biomolecular Science (IBBS), School of Pharmacy and Biomedical Sciences, University of Portsmouth, Hampshire, Portsmouth PO1 2DT, UK. Laura.Porcza@myport.ac.uk.
Claire SimmsInstitute of Biomedical and Biomolecular Science (IBBS), School of Pharmacy and Biomedical Sciences, University of Portsmouth, Hampshire, Portsmouth PO1 2DT, UK. Claire.Simms@port.ac.uk.
Mridula ChopraInstitute of Biomedical and Biomolecular Science (IBBS), School of Pharmacy and Biomedical Sciences, University of Portsmouth, Hampshire, Portsmouth PO1 2DT, UK. Mridula.Chopra@port.ac.uk.
University of Portsmouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a leading cause of death worldwide and poses a challenge to treatment. With overwhelming evidence of the role played by diet and lifestyle in cancer risk and prevention, there is a growing interest into the search for chemopreventative or chemotherapeutic agents derived from natural products. Honey is an important source of bioactive compounds derived from plants and recent years have seen an increased interest in its anticancer properties. This review examines the role of honey in targeting key hallmarks of carcinogenesis, including uncontrolled proliferation, apoptosis evasion, angiogenesis, growth factor signalling, invasion, and inflammation. The evidence for honey as an adjunct to conventional cancer therapy is also presented. The review also highlights gaps in the current understanding and concludes that, before translation of evidence from cell culture and animal studies into the clinical setting, further studies are warranted to examine the effects of honey at a molecular level, as well as on cells in the tumour environment.

Indexed as

angiogenesisapoptosiscancerfibrobalstsflavonoidhoneyinflammationinvasionphenolicproliferation

Identifiers

PMID28933410
PMCPMC5456322
OpenAlexW2526600278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.