Evidence map›Paper›PMID 28932905›Full record

ArticleParasitology research2017

Serum IgE and IgG4 against muscle larva excretory-secretory products during the early and late phases of human trichinellosis.

Marcela A Calcagno, María A Forastiero, María P Saracino, Cecilia C Vila, Stella M Venturiello

Abstract read
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Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marcela A CalcagnoMicrobiology, Immunology and Biotechnology Department, School of Pharmacy and Biochemistry, IDEHU-CONICET, Buenos Aires University, Junín 956, 1113, Buenos Aires, Argentina.
María A ForastieroMicrobiology, Immunology and Biotechnology Department, School of Pharmacy and Biochemistry, IDEHU-CONICET, Buenos Aires University, Junín 956, 1113, Buenos Aires, Argentina.
María P SaracinoMicrobiology, Immunology and Biotechnology Department, School of Pharmacy and Biochemistry, IDEHU-CONICET, Buenos Aires University, Junín 956, 1113, Buenos Aires, Argentina.
Cecilia C VilaMicrobiology, Immunology and Biotechnology Department, School of Pharmacy and Biochemistry, IDEHU-CONICET, Buenos Aires University, Junín 956, 1113, Buenos Aires, Argentina.
Stella M VenturielloMicrobiology, Immunology and Biotechnology Department, School of Pharmacy and Biochemistry, IDEHU-CONICET, Buenos Aires University, Junín 956, 1113, Buenos Aires, Argentina. sventuri@ffyb.uba.ar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In human trichinellosis, the relevance of the presence and persistence of specific serum IgE and IgG4 during the early and late phases of infection is still controversial.The aim of this work was to determine the percentage of human sera presenting IgE and IgG4 against Trichinella spiralis muscle larvae excretory-secretory products as well as their levels during the early and late phases of the infection. The antigen recognition pattern by serum total immunoglobulins (IgGAM), IgE, and IgG4 was assessed over time. Serum samples during early and late phases were analyzed by ELISA and immunoelectrotransfer blot (IETB).Results showed that (a)-IgE and IgG4 are present at constant levels in both phases; (b)-IgE recognized the glycoproteins of ~ 45 and ~ 55 kDa and IgG4 only the ~ 45 kDa;

Indexed as

AnimalsAntibodies, HelminthAntigens, HelminthBiopsyEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin EImmunoglobulin GImmunologic TestsLarvaMuscle, SkeletalTrichinella spiralisTrichinellosisAntibodies, HelminthAntigens, HelminthImmunoglobulin EImmunoglobulin GEarly phaseHuman trichinellosisIgEIgG4Immunoserological techniquesLate phase

Identifiers

PMID28932905

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.