Evidence map›Paper›PMID 28932900›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

[68Ga]Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques.

Xiang Li, Daniel Heber, Tatjana Leike, Dietrich Beitzke, Xia Lu, Xiaoli Zhang, Yongxiang Wei, Markus Mitterhauser, Wolfgang Wadsak, Saskia Kropf and 4 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of targeted chemokine receptor 4 PET/CT in evaluating active lesions in multiple myeloma, comparison toCancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  3. Review
  4. From incidental positron emission uptake toFrontiers in cardiovascular medicine · 2026
    Review
  5. Review
  6. Emerging PET radiotracers for vascular imaging.Rheumatology (Oxford, England) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Advances in PET Imaging of the CXCR4 Receptor: [Seminars in nuclear medicine · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. [Cells · 2022
    Article
  17. Accuracy of PET quantification in [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  18. Considerations on PET/MR imaging of carotid plaque inflammation withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  19. Positron Emission Tomography in Atherosclerosis Research.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Xiang LiDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. Xiang.li@meduniwien.ac.at.
Daniel HeberDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Tatjana LeikeDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Dietrich BeitzkeDivision of Cardiovascular and Interventional Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Xia LuDepartment of Nuclear Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiaoli ZhangDepartment of Nuclear Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yongxiang WeiDepartment of Nuclear Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Markus MitterhauserDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Wolfgang WadsakDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Saskia KropfScintomics GmbH, Fürstenfeldbruck, Germany.
Hans J WesterDepartment of Radiopharmaceutical Chemistry, Technische Universität München, Garching, Germany.
Christian LoeweDivision of Cardiovascular and Interventional Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Marcus HackerDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. Marcus.hacker@meduniwien.ac.at.ORCID 0000-0002-4222-4083
Alexander R HaugDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Medical University of Vienna · ATCapital Medical University · CNCenter For Biomarker Research In Medicine · ATLudwig Boltzmann Institute Applied Diagnostics · ATTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe expression of chemokine receptor type 4 (CXCR4) was found co-localized with macrophages on the atherosclerotic vessel wall and participated in the initial emigration of leukocytes. Gallium-68 [

methodsThirty-eight oncology patients underwent [

resultsThirty-four of 38 patients showed 611 focal [

conclusionPatients with high arterial uptake showed increased incidence of cardiovascular risk factors, suggesting a potential role of [

Indexed as

Coordination ComplexesMagnetic Resonance ImagingPeptides, CyclicPositron-Emission TomographyAgedFemaleHumansMaleMiddle AgedPlaque, AtheroscleroticProspective StudiesReceptors, CXCR4Reproducibility of ResultsRetrospective Studies68Ga-pentixaforCoordination ComplexesCXCR4 protein, humanPeptides, CyclicReceptors, CXCR4[68Ga]PentixaforAtherosclerosisChemokine receptor type 4PET/MRI

Identifiers

PMID28932900
PMCPMC5829117
OpenAlexW2754293947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.